Total psoriasis regression in a patient with chronic myeloid leukemia treated using nilotinib

被引：0
|
作者：
Hornak, Tomas [1 ]
Zackova, Daniela [1 ]
Mayer, Jiri [1 ]
机构：
[1] Masaryk Univ, Univ Hosp Brno, Fac Med, Dept Internal Med Hematol & Oncol, Brno, Czech Republic
来源：
ANNALS OF HEMATOLOGY | 2025年
关键词：
Chronic myeloid leukemia; Tyrosine kinase inhibitors; Nilotinib; Psoriasis; Adverse effects; INHIBITORS;
D O I：
10.1007/s00277-025-06228-x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Chronic myeloid leukemia (CML) treatment has been revolutionized over last 20 years because of tyrosine kinase inhibitors (TKIs) and patients with CML now have life expectancy of general population. Chronic TKI treatment may cause adverse effects (AEs) that vary in frequency and severity. Nilotinib shows common AEs with metabolic changes and skin AEs. Here, we present a case report of patient who experienced full psoriasis regression while treated with nilotinib. Dose reductions and an attempt to stop nilotinib treatment resulted in prompt psoriasis reappearance. This is the first documented case of positive effect of nilotinib on psoriasis.
引用
收藏
页码：2001 / 2004
页数：4
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