Keap1-Nrf2 regulate nutrient metabolism to direct CD4+T-cell activation and inflammatory functions

被引：0
|
作者：
Pyaram, Kalyani [1 ]
Tripathi, Aprajita [1 ]
Dasgupta, Debolina [1 ]
Pant, Anil [2 ]
Bugbee, Ashlyn [3 ]
机构：
[1] Univ Kansas Med Ctr, Kansas City, KS USA
[2] Texas A&M Univ, College Stn, TX USA
[3] St Jude Grad Sch Biomed Sci, Memphis, TN USA
来源：
JOURNAL OF IMMUNOLOGY | 2024年 / 212卷 / 01期
关键词：
D O I：
10.4049/jimmunol.212.supp.1250.4506
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页数：2
相关论文
共 50 条
  • [31] THE ROLE OF THE KEAP1-NRF2 ANTIOXIDANT PATHWAY IN THE CELL RESPONSE TO ANTI-LEUKEMIC THERAPY
    Michaela, Mysakova
    Kristyna, Pimkova
    Lubomir, Minarik
    Tomas, Stopka
    FREE RADICAL BIOLOGY AND MEDICINE, 2023, 201 : 57 - 57
  • [32] Development of a Cell-Permeable Cyclic Peptidyl Inhibitor against the Keap1-Nrf2 Interaction
    Salim, Heba
    Song, Jian
    Sahni, Ashweta
    Pei, Dehua
    JOURNAL OF ORGANIC CHEMISTRY, 2020, 85 (03): : 1416 - 1424
  • [33] KeaP1-Nrf2 interaction suppresses cell motility in lung adenocarcinomas by targeting the SWOP protein
    Hua, Kuo-Tai
    Kuo, Min-Liang
    CANCER RESEARCH, 2016, 76
  • [34] Splicing junction-based classifier for the detection of abnormal constitutive activation of the KEAP1-NRF2 system
    Mateos, Raul N.
    Winardi, Wira
    Chiba, Kenichi
    Okada, Ai
    Suzuki, Ayako
    Mitsuishi, Yoichiro
    Shiraishi, Yuichi
    NPJ SYSTEMS BIOLOGY AND APPLICATIONS, 2024, 10 (01)
  • [35] Development of a Splicing Junction-based Classifier for the Detection of Abnormal Activation of the KEAP1-NRF2 System
    Mateos, Raul N.
    Winardi, Wira
    Okada, Ai
    Iida, Naoko
    Nakamura, Wataru
    Sugawa, Masahiro
    Chiba, Kenichi
    Mitsuishi, Yoichiro
    Shiraishi, Yuichi
    CANCER SCIENCE, 2025, 116 : 919 - 919
  • [36] Transcriptional Dynamics of NRF2 Overexpression and KEAP1-NRF2 Inhibitors in Human Cell Line and Primary Lung Cells
    Hamblet, Corinne
    Bjorhall, Karin
    Busch, Susann
    Gehrmann, Ulf
    Oberg, Lisa
    Kubisch-Dohmen, Rebekka
    Haas, Sonja
    Aneja, Manish K.
    Geiger, Johannes
    Rudolph, Carsten
    Hornberg, Ellinor
    ANTIOXIDANTS, 2024, 13 (08)
  • [37] Altered T cell homeostasis and activation in HIV-1 elite suppressors with low CD4+T-cell counts
    Groves, K. C.
    Bibby, D.
    Isaksen, A.
    Deayton, J.
    Anderson, J.
    Orkin, C.
    Stagg, A. J.
    McKnight, A.
    RETROVIROLOGY, 2009, 6
  • [38] Antioxidation protein Nrf2 modulates glutamine metabolism to regulate activation-driven expansion of CD4+T-cells
    Tripathi, Aprajita
    Pant, Anil
    Bugbee, Ashlyn
    Choi, Ben H.
    Pyaram, Kalyani
    JOURNAL OF IMMUNOLOGY, 2023, 210 (01):
  • [39] Sitagliptin treatment of patients with type 2 diabetes does not affect CD4+T-cell activation
    White, Perrin C.
    Chamberlain-Shea, Heidi
    de la Morena, Maria-Teresa
    JOURNAL OF DIABETES AND ITS COMPLICATIONS, 2010, 24 (03) : 209 - 213
  • [40] Visualization of protein interactions on chromatin illumines novel functions for the Keap1-Nrf2 xenobiotic response signaling in Drosophila
    Deng, H.
    Kerppola, T.
    MOLECULAR BIOLOGY OF THE CELL, 2015, 26
12345