Radiopharmaceuticals for Pancreatic Cancer: A Review of Current Approaches and Future Directions

被引：0
作者：
Calistri, Sara [1 ,2 ]
Ottaviano, Giuseppe [2 ]
Ubaldini, Alberto [2 ]
机构：
[1] Univ Bologna, Alma Mater Studiorum, Dept Pharm & Biotechnol, I-40126 Bologna, Italy
[2] CR Bologna, Italian Natl Agcy New Technol Energy & Sustainable, ENEA, Via Martiri Monte Sole 4, I-40129 Bologna, Italy
来源：
PHARMACEUTICALS | 2024年 / 17卷 / 10期
关键词：
radiopharmaceuticals; pancreatic cancer; radionuclides; PRRT; NETs; RECEPTOR RADIONUCLIDE THERAPY; NEUROENDOCRINE TUMORS; BREAST-CANCER; GREEN NANOTECHNOLOGY; RADIATION; ADENOCARCINOMA; TARGET; CELLS; AUGER; FUNDAMENTALS;
D O I：
10.3390/ph17101314
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The poor prognosis of pancreatic cancer requires novel treatment options. This review examines the evolution of radiopharmaceuticals in the treatment of pancreatic cancer. Established strategies such as peptide receptor radionuclide therapy (PRRT) offer targeted and effective treatment, compared to conventional treatments. However, there are currently no radiopharmaceuticals approved for the treatment of pancreatic cancer in Europe, which requires further research and novel approaches. New radiopharmaceuticals including radiolabeled antibodies, peptides, and nanotechnological approaches are promising in addressing the challenges of pancreatic cancer therapy. These new agents may offer more specific targeting and potentially improve efficacy compared to traditional therapies. Further research is needed to optimize efficacy, address limitations, and explore the overall potential of these new strategies in the treatment of this aggressive and harmful pathology.
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页数：21
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