Bacteremia and meningitis caused by penicillin-resistant Streptococcus pneumoniae serotype 35B successfully treated with ceftriaxone combined with vancomycin followed by linezolid: A case report

被引：0

作者：

Tomioka, Mifumi ^{[1
]}

Nakamura, Kiwamu ^{[2
]}

Duan, Shaoqing ^{[3
]}

Matsumoto, Kazuaki ^{[3
]}

Shindo, Takahiro ^{[1
]}

Hoshi, Keisuke ^{[1
]}

Nagao, Mika ^{[1
]}

Oshima, Fuminari ^{[4
]}

Hara, Yasuka ^{[5
]}

Namai, Yoshiyuki ^{[1
]}

机构：

[1] Ohta Nishinouchi Hosp, Dept Pediat, Koriyama, Japan

[2] Iwate Med Univ, Dept Internal Med, Lab Med & Infect Dis, Morioka, Japan

[3] Keio Univ, Dept Pharmacol, Tokyo, Japan

[4] Ohta Nishinouchi Hosp, Dept Pharmacol, Koriyama, Japan

[5] Fukushima Med Univ Hosp, Infect Control Unit, Fukushima, Japan

来源：

INTERNAL MEDICINE | 2024年

关键词：

PRSP; linezolid; meningitis; pneumococcal vaccine; BACTERIAL-MENINGITIS; JAPAN;

D O I：

10.2169/internalmedicine.3904-24

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We herein report a case of bacterial meningitis and bacteremia in a 3-month-old boy caused by Streptococcus pneumoniae serotype 35B multidrug resistance. Intravenous ampicillin was administered on admission. However, when pneumococcal meningitis was suspected, the antibiotic treatment was changed to ceftriaxone (CTRX) and vancomycin (VCM). However, owing to difficulties in achieving sufficient serum trough levels of VCM, this treatment was again switched to linezolid (LZD). The patient recovered without complications after 16 days of CTRX and LZD treatment. This case suggests that LZD is a viable treatment option for bacterial meningitis.

引用

页数：6

共 22 条

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