Human Immunodeficiency Virus Type 2 (HIV-2) EU-Supporting Standardized HIV-2 Drug Resistance Interpretation: An Update

被引:0
作者
Charpentier, Charlotte [1 ,2 ]
Berzow, Dirk [3 ,4 ]
Le Hingrat, Quentin [1 ,2 ]
Kaiser, Rolf [5 ,6 ,7 ]
Gomes, Perpetua [8 ,9 ]
Miranda, Ana Claudia [10 ]
Damond, Florence [1 ,2 ]
Ghosn, Jade [1 ,11 ]
van Kampen, Jeroen J. A. [12 ]
Jensen, Bjoern-Erik Ole [13 ,14 ]
Boehm, Michael [5 ,6 ,7 ]
Wensing, Annemarie M. J. [15 ]
Descamps, Diane [1 ,2 ]
Obermeier, Martin [4 ,16 ]
机构
[1] Univ Paris Cite, INSERM, IAME, UMR 1137, Paris, France
[2] Hop Bichat Claude Bernard, AP HP, Serv Virol, Paris, France
[3] Praxis Infectiol, Hamburg, Germany
[4] Deutsch Arbeitsgemeinschaft Niedergelassener Arzte, Berlin, Germany
[5] Univ Cologne, Fac Med, Cologne, Germany
[6] Univ Cologne, Univ Hosp Cologne, Inst Virol, Cologne, Germany
[7] Deutsch AIDS Gesell eV DAIG, Essen, Germany
[8] Hosp Egas Moniz Lisbon, Serv Patol Clin, Unidade Local Saude Lisboa Ocidental, Lab Biol Mol, Lisbon, Portugal
[9] Egas Moniz Ctr Interdisciplinary Res CiiEM, Egas Moniz Sch Hlth & Sci, Almada, Portugal
[10] Hosp Egas Moniz, Doencas Infeciosas, Unidade Local Saude Lisboa Ocidental, Lisbon, Portugal
[11] Hop Bichat Claude Bernard, AP HP, Serv Malad Infect & Trop, Paris, France
[12] Erasmus MC, Dept Viroscience, Rotterdam, Netherlands
[13] Heinrich Heine Univ, Med Fac, Dept Gastroenterol Hepatol & Infect Dis, Dusseldorf, Germany
[14] Heinrich Heine Univ, Univ Hosp Dusseldorf, Dusseldorf, Germany
[15] Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Dept Global Publ Hlth & Bioeth, Utrecht, Netherlands
[16] MVZ Med Infekt Zentrum Berlin, Berlin, Germany
关键词
HIV-2; drug-resistance rules; Internet tool; update; VITRO PHENOTYPIC SUSCEPTIBILITY; REVERSE-TRANSCRIPTASE; INTEGRASE INHIBITORS; RALTEGRAVIR; MUTATIONS; SIV;
D O I
10.1093/cid/ciaf110
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Human immunodeficiency virus type 2 (HIV-2) is an attenuated retroviral infection characterized by specific natural susceptibility to antiretroviral drugs and acquired resistance profiles. Based on the latest knowledge of phenotypic data and clinical follow-up, HIV-2 resistance interpretation rules have been updated and implemented in a freely available resistance analysis tool.
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