Nanoparticle-Based Approaches in the Diagnosis and Treatment of Brain Tumors

被引:2
作者
Pourmasoumi, Parvin [1 ,2 ]
Banihashemian, Seyed Abdolvahab [1 ,2 ]
Zamani, Farshid [3 ]
Rasouli-Nia, Aghdass [4 ]
Mehrabani, Davood [4 ,5 ,6 ,7 ]
Karimi-Busheri, Feridoun [4 ]
机构
[1] Islamic Azad Univ, Dept Biomed Engn, Cent Tehran Branch, Tehran 193951495, Iran
[2] Islamic Azad Univ, Stem Cells Res Ctr, Tissue Engn & Regenerat Med Inst, Cent Tehran Branch, Tehran 1477893780, Iran
[3] Shahid Beheshti Univ Med Sci, Sch Med, Dept Immunol, Tehran 1983969411, Iran
[4] Univ Alberta, Fac Med, Dept Oncol, Edmonton, AB T6G 1Z2, Canada
[5] Shiraz Univ Med Sci, Stem Cell Technol Res Ctr, Shiraz 7134814336, Iran
[6] Shiraz Univ Med Sci, Burn & Wound Healing Res Ctr, Shiraz 7134814336, Iran
[7] Shiraz Univ Med Sci, Comparat & Expt Med Ctr, Shiraz 7134814336, Iran
关键词
brain tumor; neuro-oncology; Glioblastoma multiforme; nanoparticle; treatment; WALLED CARBON NANOTUBES; CELL-PENETRATING PEPTIDE; IN-VITRO; EXTRACELLULAR VESICLES; MULTIFUNCTIONAL NANOPARTICLES; GOLD NANOPARTICLES; TARGETED DELIVERY; STEM-CELLS; THERAPY; GLIOMA;
D O I
10.3390/jcm13237449
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Glioblastomas are highly invasive brain tumors among perilous diseases. They are characterized by their fast proliferation and delayed detection that render them a significant focal point for medical research endeavors within the realm of cancer. Among glioblastomas, Glioblastoma multiforme (GBM) is the most aggressive and prevalent malignant brain tumor. For this, nanomaterials such as metallic and lipid nanoparticles and quantum dots have been acknowledged as efficient carriers. These nano-materials traverse the blood-brain barrier (BBB) and integrate and reach the necessary regions for neuro-oncology imaging and treatment purposes. This paper provides a thorough analysis on nanoparticles used in the diagnosis and treatment of brain tumors, especially for GBM.
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页数:25
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