Background: Virtual care is increasingly incorporated within routine health care settings to improve patient experience andaccess to care. A patient's experience encompasses all the interactions an individual has with the health care system. This includesa greater emphasis on actively involving carers in the decisions and activities surrounding a patient's health care. Objective: This study aimed to investigate the variety of health care delivery challenges encountered in a virtual hospital andexplore potential ways to improve the patient experience.Methods: Focusing on acute respiratory, this protocol outlines a mixed methods study exploring the patient experience of avirtual hospital in Australia, Royal Prince Alfred Virtual Hospital (rpavirtual). We will use an exploratory mixed methods approachcomprising of secondary data analysis, observations, interviews, and co-design focus groups. Participants will include patients,their carers, and health care workers who are involved in the acute respiratory virtual hospital model of care. Together, the datawill be triangulated to explore views and experiences of using this model of care, as well as co-designing recommendations forfurther improvement. Results: Findings from this study will identify current barriers and facilitators to implementing virtual care, such as work-as-doneversus work-as-imagined, equity of care, the role of carers, and patient safety during virtual care. As of August 2024, a total of25 participants have been interviewed. Conclusions: This protocol outlines a mixed methods case study on the acute respiratory model of care from Australia's firstvirtual hospital, rpavirtual. This study will collect the experiences of patients, carers, and health care workers to co-design a seriesof recommendations to improve the patient experience