The therapeutic potential of Honeysuckle in cardiovascular disease: an anti-inflammatory intervention strategy

被引:3
作者
Zhao, Yue [1 ]
Zhang, Jiale [2 ,4 ]
Lu, Fei [3 ]
Xu, Weiming [2 ,4 ]
Ma, Qingxiao [5 ]
Hu, Jingqing [1 ,2 ,6 ]
机构
[1] Changchun Univ Chinese Med, Changchun, Jilin, Peoples R China
[2] China Acad Chinese Med Sci, Inst Basic Theory Chinese Med, Beijing, Peoples R China
[3] Liaoning Univ Tradit Chinese Med, Affiliated Hosp 2, Shenyang, Liaoning, Peoples R China
[4] China Sci & Technol Dev Ctr Chinese Med, Beijing, Peoples R China
[5] China Natl Hlth Dev Res Ctr, Beijing, Peoples R China
[6] Tianjin Univ Tradit Chinese Med, 10 Poyang Lake Rd, Tianjin 301617, Peoples R China
来源
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH | 2024年 / 16卷 / 12期
基金
国家重点研发计划;
关键词
Honeysuckle; anti-inflammatory; cardiovascular disease; review; C-REACTIVE PROTEIN; CHLOROGENIC ACID; FERULIC ACID; INFLAMMATORY RESPONSE; NLRP3; INFLAMMASOME; CAFFEIC ACID; ENDOTHELIAL FUNCTION; SIGNALING PATHWAY; DOWN-REGULATION; NF-KB;
D O I
10.62347/NJMJ7853
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Honeysuckle is a conventional Chinese medicine with several therapeutic applications. With the advancement of modern scientific technologies, Honeysuckle's pharmacological effects and medicinal properties have been investigated more thoroughly. Studies demonstrate that the bioactive compounds in Honeysuckle possess anti-inflammatory effects via several mechanisms, protecting the cardiovascular system. This article provides a reference for the clinical use of Honeysuckle by reviewing research on the therapeutic impact of Honeysuckle and its active constituents on cardiovascular diseases, such as coronary atherosclerotic heart disease (CHD), myocardial ischemia-reperfusion (MI/R), acute myocardial infarction (AMI), hypertension, arrhythmia, and heart failure, through the inhibition of inflammatory responses.
引用
收藏
页码:7262 / 7277
页数:16
相关论文
共 124 条
[1]   Cardio-protective and antioxidant properties of caffeic acid and chlorogenic acid: Mechanistic role of angiotensin converting enzyme, cholinesterase and arginase activities in cyclosporine induced hypertensive rats [J].
Agunloye, Odunayo Michael ;
Oboh, Ganiyu ;
Ademiluyi, Adedayo Oluwaseun ;
Ademosun, Ayokunle Olubode ;
Akindahunsi, Akintunde Afolabi ;
Oyagbemi, Ademola Adetokunbo ;
Omobowale, Temidayo Olutayo ;
Ajibade, Temitayo Olabisi ;
Adedapo, Adeolu Alex .
BIOMEDICINE & PHARMACOTHERAPY, 2019, 109 :450-458
[2]   Myocardial ischemia-reperfusion injury and the influence of inflammation  [J].
Algoet, Michiel ;
Janssens, Stefan ;
Himmelreich, Uwe ;
Gsell, Willy ;
Pusovnik, Matic ;
van den Eynde, Jef ;
Oosterlinck, Wouter .
TRENDS IN CARDIOVASCULAR MEDICINE, 2023, 33 (06) :357-366
[3]  
Alwi I, 2019, ACTA MED INDONES, V51, P287
[4]  
[Anonymous], 61. Dengue - PAHO/WHO | Pan American Health Organization. Accessed December 1, 2021$4. https://www.paho.org/en/topics/dengue
[5]   Acute Coronary Events [J].
Arbab-Zadeh, Armin ;
Nakano, Masataka ;
Virmani, Renu ;
Fuster, Valentin .
CIRCULATION, 2012, 125 (09) :1147-1156
[6]   The role of inflammation in the pathogenesis and treatment of arrhythmias [J].
Armbruster, Anastasia L. ;
Campbell, Kristen Bova ;
Kahanda, Milan G. ;
Cuculich, Phillip S. .
PHARMACOTHERAPY, 2022, 42 (03) :250-262
[7]   Myocardial Ischemia/Reperfusion Injury Is Mediated by Leukocytic Toll-Like Receptor-2 and Reduced by Systemic Administration of a Novel Anti-Toll-Like Receptor-2 Antibody [J].
Arslan, Fatih ;
Smeets, Mirjam B. ;
O'Neill, Luke A. J. ;
Keogh, Brian ;
McGuirk, Peter ;
Timmers, Leo ;
Tersteeg, Claudia ;
Hoefer, Imo E. ;
Doevendans, Pieter A. ;
Pasterkamp, Gerard ;
de Kleijn, Dominique P. V. .
CIRCULATION, 2010, 121 (01) :80-90
[8]   Chlorogenic acid attenuates high-carbohydrate, high-fat diet-induced cardiovascular, liver, and metabolic changes in rats [J].
Bhandarkar, Nikhil S. ;
Brown, Lindsay ;
Panchal, Sunil K. .
NUTRITION RESEARCH, 2019, 62 :78-88
[9]   Quercetin attenuates atherosclerotic inflammation and adhesion molecule expression by modulating TLR-NF-κB signaling pathway [J].
Bhaskar, Shobha ;
Sudhakaran, P. R. ;
Helen, A. .
CELLULAR IMMUNOLOGY, 2016, 310 :131-140
[10]   Quercetin modulates toll-like receptor-mediated protein kinase signaling pathways in oxLDL-challenged human PBMCs and regulates TLR-activated atherosclerotic inflammation in hypercholesterolemic rats [J].
Bhaskar, Shobha ;
Helen, A. .
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2016, 423 (1-2) :53-65