Case Report: Clinical and Pathological Findings of Tuberculous Gumma: A Case Report and Literature Review

被引:0
作者
Deng, Li-Jia [1 ]
Ye, Qian [1 ,2 ]
Luo, Si-Yu [1 ]
Wang, Qin-Xiao [1 ]
Fang, Sheng [1 ]
机构
[1] Chongqing Med Univ, Dept Dermatol, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400016, Peoples R China
[2] Chinese Acad Med Sci, Plast Surg Hosp, Dept Dermatol, Peking Union Med Coll, Beijing, Peoples R China
关键词
PATIENT; ABSCESSES;
D O I
10.4269/ajtmh.23-0510
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Tuberculous gumma (TG) is a rare type of cutaneous tuberculosis thought to occur as a result of the hematogenous spread of Mycobacterium tuberculosis, which is more common in immunosuppressed individuals. An 8-year-old boy presented with a 2-month history of multiple indolent enlarging ulcerated nodules on his left upper extremity. He had a past medical history of bacille Calmette-Guerin vaccine induced lupus vulgaris. Skin biopsy of the nodules showed granulomas and neutrophil-dominated purulent inflammation. Ziehl-Neelsen staining was negative, and the cultures were positive for M. tuberculosis. Furthermore, the M. tuberculosis complex was identified using metagenomic next-generation sequencing. Standard antitubercular therapy was started at full doses, and the skin lesions had significantly improved 3 months later. Here we review the literature since 2000 and describe the clinical and pathological features of TG.
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页码:805 / 808
页数:4
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