The YBa2Cu3O7-delta (YBCO)-coated conductors (CCs) exhibit great potential in the manufacturing of ultrahigh field magnets, superconducting fault current limiter, etc., while the irreversible strain plays a crucial role in designing and optimizing the superconducting devices. However, it is a big challenge to obtain the strain dependence of critical current (Ic) of the coated conductor YBCO CC (width = 10mm, critical current >500A) because of easy destruction induced by strain concentration near the grips in the process of tension. In addition, factors such as non-uniform deformation, contact resistance, and even mechanoelectrical coupling effect, which can induce non-uniform performance degradation, will be huge barriers against the accurate measurement of irreversible strain. In this paper, the failure phenomena and inducement analysis are studied, and an optimized experimental program is proposed based on the test and finite element analysis, which reduces the measuring errors caused by some unfavorable factors. At the end, the complete electrical performance degradation curve of YBCO CC with high I-c is given.