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Nonobese young females with polycystic ovary syndrome are at high risk for long-term cardiovascular disease
被引:1
作者:

Zhao, Xingping
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Cent South Univ, Clin Res Ctr, Xiangya Hosp 3, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China
Cent South Univ, Dept Gynecol, Xiangya Hosp 3, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China Cent South Univ, Clin Res Ctr, Xiangya Hosp 3, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China

Wang, Jie
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Cent South Univ, Clin Res Ctr, Xiangya Hosp 3, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China
Cent South Univ, Xiangya Hosp 3, Dept Cardiol, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China Cent South Univ, Clin Res Ctr, Xiangya Hosp 3, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China

Sun, Dan
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机构:
Cent South Univ, Dept Gynecol, Xiangya Hosp 3, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China
Guangxi Med Univ, Dept Gynecol & Obstet, Affiliated Hosp 1, Nanning, Peoples R China Cent South Univ, Clin Res Ctr, Xiangya Hosp 3, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China

Xu, Dabao
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Cent South Univ, Dept Gynecol, Xiangya Hosp 3, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China Cent South Univ, Clin Res Ctr, Xiangya Hosp 3, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China

Lu, Yao
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h-index: 0
机构:
Cent South Univ, Clin Res Ctr, Xiangya Hosp 3, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China
Cent South Univ, Xiangya Hosp 3, Dept Cardiol, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China
Kings Coll London, Fac Life Sci & Med, 150 Stamford St, London SE1 9NH, England Cent South Univ, Clin Res Ctr, Xiangya Hosp 3, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China
机构:
[1] Cent South Univ, Clin Res Ctr, Xiangya Hosp 3, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China
[2] Cent South Univ, Dept Gynecol, Xiangya Hosp 3, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China
[3] Cent South Univ, Xiangya Hosp 3, Dept Cardiol, 138 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China
[4] Guangxi Med Univ, Dept Gynecol & Obstet, Affiliated Hosp 1, Nanning, Peoples R China
[5] Kings Coll London, Fac Life Sci & Med, 150 Stamford St, London SE1 9NH, England
基金:
中国国家自然科学基金;
关键词:
Cardiovascular disease;
Polycystic ovary syndrome;
Proteome;
DCBLD2;
SYNDROME PCOS;
WOMEN;
HYPERANDROGENISM;
MORTALITY;
D O I:
10.1093/eurjpc/zwae375
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
This study provides comprehensive evidence for the association between PCOS and CVD by using UK Biobank data. Patients with PCOS, especially young nonobese patients, have an increased risk of CVD, and this vulnerable population should receive increased attention in the future. Clarifying this condition specific to female which can increase CVD risk is warranted to inform gender-related prevention and management of CVD. We need to further improve CVD risk management in the females with PCOS, and DCBLD2 can be potentially used as a CVD biomarker for patients with PCOS.
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2018, 14 (05)
:270-284

Escobar-Morreale, Hector F.
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机构:
Hosp Univ Ramon y Cajal, Dept Endocrinol & Nutr, Madrid, Spain
Univ Alcala, Alcala De Henares, Spain
Ctr Invest Biomed Red Diabet & Enfermedades Metab, Madrid, Spain
IRYCIS, Madrid, Spain Hosp Univ Ramon y Cajal, Dept Endocrinol & Nutr, Madrid, Spain