Comprehensive comparison of two colour varieties of Perillae folium by UHPLC-Q-TOF/MS analysis combining with feature-based molecular networking

被引：3

作者：

Chen, Jiabao ^{[1
,2
,3
]}

Wang, Xiufang ^{[1
,2
,3
,5
]}

Xin, Xiaodong ^{[1
,2
,3
]}

Zheng, Yuguang ^{[1
,4
,5
,6
]}

Hou, Fangjie ^{[4
,5
]}

Li, Chunhua ^{[1
,2
]}

Guo, Long ^{[1
,4
,5
]}

Wang, Lei ^{[1
,4
,5
]}

机构：

[1] Hebei Univ Chinese Med, Coll Pharm, Shijiazhuang, Hebei, Peoples R China

[2] Hebei Technol Innovat Ctr TCM Formula Preparat, Shijiazhuang 050091, Peoples R China

[3] Hebei Higher Educ Appl Technol Res Ctr TCM Dev & I, Shijiazhuang, Peoples R China

[4] Tradit Chinese Med Proc Technol Innovat Ctr Hebei, Shijiazhuang, Peoples R China

[5] Int Joint Res Ctr Resource Utilizat & Qual Evaluat, Shijiazhuang, Peoples R China

[6] Hebei Chem & Pharmaceut Coll, Shijiazhuang, Peoples R China

来源：

FOOD CHEMISTRY | 2025年 / 463卷

关键词：

LC-MS; Chemical annotation; Multivariate statistical analysis; Perilla frutescens (L.) Britt; EXTRACT; ANTHOCYANINS; ANTIOXIDANT;

D O I：

10.1016/j.foodchem.2024.141293

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Perillae Folium (PF), the leaf of Perilla frutescens (L.) Britt is extensively used as a culinary vegetable and medicinal herb in many countries. Purple PF (P. frutescens var. arguta) and green PF (P. frutescens var. frutescens) are two of the main varieties. In this study, UHPLC-Q-TOF/MS assisted with feature-based molecular networking (FBMN) was applied for chemical characterization. In total, 82 metabolites, mainly phenolic acid derivatives were identified from PF. With the help of FBMN, five organic acid glucosides together with three N-phenylpropenoyl-L-amino acids (NPAs) were identified in PF for the first time. Multivariate statistical methods were utilized for comprehensive comparison of purple and green PF profiles. 12 compounds with their relative contents varied significantly between purple and green PF were screened out. Overall, the present study offers valuable insights for chemical elucidation of PF which would be helpful for comprehensive utilization of PF resource.

引用

页数：16

共 28 条

[1] Ethnomedicinal, Phytochemical and Pharmacological Investigations of Perilla frutescens (L.) Britt. [J].

Ahmed, Hiwa M. .

MOLECULES, 2019, 24 (01)

[2] Antioxidant and anti proliferative activities of phytochemicals from Quince (Cydonia vulgaris) peels [J].

Alesiani, Daniela ;

Canini, Antonella ;

D'Abrosca, Brigida ;

DellaGreca, Marina ;

Fiorentino, Antonio ;

Mastellone, Claudio ;

Monaco, Pietro ;

Pacifico, Severina .

FOOD CHEMISTRY, 2010, 118 (02) :199-207

[3] Characterization, identification, and quantification of phenolic compounds using UPLC-Q-TOF-MS and evaluation of antioxidant activity of 73 Perilla frutescens accessions [J].

Assefa, Awraris Derbie ;

Jeong, Yi-Jin ;

Kim, Da-Jeong ;

Jeon, Young-Ah ;

Ok, Hyun-Choong ;

Baek, Hyung-Jin ;

Sung, Jung-Sook .

FOOD RESEARCH INTERNATIONAL, 2018, 111 :153-167

[4] Screening of Anti-Lipase Components of Artemisia argyi Leaves Based on Spectrum-Effect Relationships and HPLC-MS/MS [J].

Chang, Yaqing ;

Zhang, Dan ;

Yang, Guiya ;

Zheng, Yuguang ;

Guo, Long .

FRONTIERS IN PHARMACOLOGY, 2021, 12

[5] Metabolomic profiling of developing perilla leaves reveals the best harvest time [J].

Chen, Jiabao ;

Guo, Long ;

Yang, Guiya ;

Yang, Aitong ;

Zheng, Yuguang ;

Wang, Lei .

FRONTIERS IN PLANT SCIENCE, 2022, 13

[6] Comprehensive Comparison of Two Color Varieties of Perillae Folium by GC-MS-Based Metabolomic Approach [J].

Chen, Jiabao ;

Zhang, Dan ;

Wang, Qian ;

Yang, Aitong ;

Zheng, Yuguang ;

Wang, Lei .

MOLECULES, 2022, 27 (20)

[7] Quantitative Comparison and Chemical Profile Analysis of Different Medicinal Parts of Perilla frutescens (L.) Britt. from Different Varieties and Harvest Periods [J].

Fan, Yuqi ;

Cao, Xiunan ;

Zhang, Mengmeng ;

Wei, Shujie ;

Zhu, Yameng ;

Ouyang, Huizi ;

He, Jun .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2022, 70 (28) :8838-8853

[8] Feature-Based Molecular Networking Discovery of Bromopyrrole Alkaloids from the Marine Sponge Agelas dispar [J].

Freire, Vitor F. ;

Gubiani, Juliana R. ;

Spencer, Tara M. ;

Hajdu, Eduardo ;

Ferreira, Antonio G. ;

Ferreira, Dayana A. S. ;

de Castro Levatti, Erica, V ;

Burdette, Joanna E. ;

Camargo, Carlos Henrique ;

Tempone, Andre G. ;

Berlinck, Roberto G. S. .

JOURNAL OF NATURAL PRODUCTS, 2022, 85 (05) :1340-1350

[9] Anthocyanins in perilla plants and dried leaves [J].

Fujiwara, Yumi ;

Kono, Miya ;

Ito, Airi ;

Ito, Michiho .

PHYTOCHEMISTRY, 2018, 147 :158-166

[10] Characterization of Anthocyanins in Perilla frutescens var. acuta Extract by Advanced UPLC-ESI-IT-TOF-MSn Method and Their Anticancer Bioactivity [J].

He, Yan-Kang ;

Yao, You-Yuan ;

Chang, Ya-Ning .

MOLECULES, 2015, 20 (05) :9155-9169

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