Serological and molecular investigation of Leptospira spp. In bats (Chiroptera, Mammalia) from Brazil

被引：0

作者：

Batista, Juliana Maria Nunes ^{[1
]}

Guedes, Israel Barbosa ^{[1
]}

Vila, Emmanuel Messias ^{[3
]}

Jorge, Felipe Rodrigues ^{[4
]}

Esteves, Stephanie Bergmann ^{[1
]}

Brito, Joao Eduardo Cavalcanti ^{[2
]}

Gaeta, Natalia Carrillo ^{[1
,6
]}

de Mello, Beatriz Gagete Verissimo ^{[2
]}

Mori, Enio ^{[5
]}

Cortez, Adriana ^{[6
]}

Dias, Ricardo Augusto ^{[2
]}

Neto, Jose Soares Ferreira ^{[1
]}

Heinemann, Marcos Bryan ^{[1
]}

机构：

[1] Univ Sao Paulo, Lab Zoonoses Bacterianas, Dept Med Vet Prevent & Saude Anim, Fac Med Vet & Zootecnia, Sao Paulo, SP, Brazil

[2] Univ Sao Paulo, Lab Epidemiol & Bioestat, Dept Med Vet Prevent & Saude Anim, Fac Med Vet & Zootecnia, Sao Paulo, SP, Brazil

[3] Univ Fed Paraiba, Dept Sistemat & Ecol, Lab Mamiferos, CCEN DSE, Joao Pessoa, Paraiba, Brazil

[4] Univ Estadual Ceara UECE, Sobral, Ceara, Brazil

[5] Inst Pasteur, Sao Paulo, SP, Brazil

[6] Univ Santo Amaro UNISA, Sao Paulo, SP, Brazil

来源：

MICROBIAL PATHOGENESIS | 2025年 / 198卷

基金：

巴西圣保罗研究基金会;

关键词：

Chiroptera; Bacterial zoonoses; Leptospirosis; Public health; SAO-PAULO; TRANSMISSION; STATE;

D O I：

10.1016/j.micpath.2024.107117

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Bats play a crucial role in the ecosystem, yet concerns have arisen regarding their potential as carriers of zoonotic bacteria, including Leptospira spp. Due to the lack of knowledge about the carrier state of bats in Brazil, this study aimed to evaluate the presence of antibodies against Leptospira spp. and its DNA in bats from four Brazilian States (Sao Paulo, Paraiba, Pernambuco, and Ceara<acute accent>). Bats were captured using mist nets and categorized by sex, age, and species. Antibodies were searched in 22 bats via the microscopic agglutination test (MAT). Additionally, 168 kidney and nine urine samples were subjected to PCR for Leptospira spp. Out of 177 samples tested, two (1.13 %) were positive in PCR, while none showed reactivity in MAT. These results suggest a low prevalence of Leptospira spp. infection in bats, indicating a limited role in transmitting leptospirosis to humans, domestic animals, and wildlife in the studied region.

引用

页数：5

共 40 条

[1] Leprospira and leptospirosis [J].

Adler, Ben ;

de la Pena Moctezuma, Alejandro .

VETERINARY MICROBIOLOGY, 2010, 140 (3-4) :287-296

[2] Development and Validation of a Real-Time PCR for Detection of Pathogenic Leptospira Species in Clinical Materials [J].

Ahmed, Ahmed ;

Engelberts, Mirjam F. M. ;

Boer, Kimberly R. ;

Ahmed, Niyaz ;

Hartskeerl, Rudy A. .

PLOS ONE, 2009, 4 (09)

[3]

Beltz LA, 2018, Bats and Human Health: Ebola, SARS, Rabies and beyond, DOI 10.1002/9781119150060

[4] Leptospirosis: a zoonotic disease of global importance [J].

Bharti, AR ;

Nally, JE ;

Ricaldi, JN ;

Matthias, MA ;

Diaz, MM ;

Lovett, MA ;

Levett, PN ;

Gilman, RH ;

Willig, MR ;

Gotuzzo, E ;

Vinetz, JM .

LANCET INFECTIOUS DISEASES, 2003, 3 (12) :757-771

[5]

Bianconi Gledson Vigiano, 2004, Rev. Bras. Zool., V21, P943, DOI 10.1590/S0101-81752004000400032

[6] A systematic review of Leptospira in water and soil environments [J].

Bierque, Emilie ;

Thibeaux, Roman ;

Girault, Dominique ;

Soupe-Gilbert, Marie-Estelle ;

Goarant, Cyrille .

PLOS ONE, 2020, 15 (01)

[7]

Bredt A., 2012, Plantas e morcegos na recuperacao de areas degradadas e na paisagem urbana

[8] Bats (Mammalia: Chiroptera) in urban-rural interfaces: community structure associated with pathogen screening in Sao Paulo-the largest metropolitan region in Brazil [J].

Brito, Joao Eduardo Cavalcanti ;

de Mello, Beatriz Gagete Verissimo ;

Gaeta, Natalia Carrillo ;

Batista, Juliana Maria Nunes ;

Brito, Tiago Roberto ;

Agostinho, Washington Carlos ;

Brandao, Paulo Eduardo ;

Heinemann, Marcos Bryan ;

Dias, Ricardo Augusto .

VETERINARY RESEARCH COMMUNICATIONS, 2023, 47 (03) :1575-1600

[9] A century of Leptospira strain typing [J].

Cerqueira, Gustavo M. ;

Picardeau, Mathieu .

INFECTION GENETICS AND EVOLUTION, 2009, 9 (05) :760-768

[10] Insight into the Epidemiology of Leptospirosis: A Review of Leptospira Isolations from "Unconventional" Hosts [J].

Cilia, Giovanni ;

Bertelloni, Fabrizio ;

Albini, Sara ;

Fratini, Filippo .

ANIMALS, 2021, 11 (01) :1-16

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