Emerging MRI biomarkers for the diagnosis of multiple sclerosis

被引：4

作者：

Maggi, Pietro ^{[1
]}

Absinta, Martina ^{[2
,3
]}

机构：

[1] Catholic Univ Louvain, Inst Neurosci, Neuroinflammat Imaging Lab NIL, Ave E Mounier 53, B-1200 Brussels, Belgium

[2] Humanitas Univ, Dept Biomed Sci, Via Rita levi Montalcini, I-20072 Milan, Italy

[3] IRCCS Humanitas Res Hosp, Neuro Ctr, Expt Neuropathol Lab, Milan, Italy

来源：

MULTIPLE SCLEROSIS JOURNAL | 2024年 / 30卷 / 14期

关键词：

Multiple sclerosis; differential diagnosis; central vein sign; paramagnetic rim lesions; cortical lesions; imaging biomarkers; CENTRAL VEIN SIGN; ENHANCEMENT; IMPROVES; LESIONS; MATTER;

D O I：

10.1177/13524585241293579

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The need to improve diagnostic precision in multiple sclerosis (MS) is widely recognized. In recent years, several novel magnetic resonance imaging (MRI) biomarkers have been proposed to enhance diagnostic specificity and reduce misdiagnosis. Some of these imaging biomarkers are deemed highly specific for MS and are likely ready to enter the MS diagnostic work-up, while others are still in their exploratory phase. In addition, new synthetic MRI contrasts and artificial intelligence-based diagnostic algorithms are being tested to reduce the time burden related to imaging data acquisition and analysis. In this review, we summarize the most recent advancement in the field, focusing on the adoption of these novel MRI biomarkers-whether used alone or in combination-for the differential diagnosis of MS.

引用

页码：1704 / 1713

页数：10

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