Audiological Features in Patients with Rheumatoid Arthritis: A Systematic Review

被引:3
作者
Chen, Jiann-Jy [1 ,2 ]
Hsu, Chih-Wei [3 ,4 ]
Chen, Yen-Wen [1 ]
Chen, Tien-Yu [5 ,6 ]
Zeng, Bing-Syuan [7 ,8 ]
Tseng, Ping-Tao [1 ,7 ,9 ,10 ]
机构
[1] Prospect Clin Otorhinolaryngol & Neurol, Kaohsiung 811026, Taiwan
[2] I Shou Univ, E Da Canc Hosp, Dept Otorhinolaryngol, Kaohsiung 824005, Taiwan
[3] Kaohsiung Chang Gung Mem Hosp, Dept Psychiat, Kaohsiung 833401, Taiwan
[4] Chang Gung Univ, Coll Med, Kaohsiung 833401, Taiwan
[5] Triserv Gen Hosp, Natl Def Med Ctr, Sch Med, Dept Psychiat, Taipei 114202, Taiwan
[6] Natl Yang Ming Chiao Tung Univ, Inst Brain Sci, Taipei 112, Taiwan
[7] Natl Sun Yat Sen Univ, Inst Biomed Sci, Kaohsiung 80424, Taiwan
[8] I Shou Univ, E Da Canc Hosp, Dept Internal Med, Kaohsiung 824005, Taiwan
[9] Asia Univ, Coll Med & Hlth Sci, Dept Psychol, Taichung 413305, Taiwan
[10] Natl Sun Yat Sen Univ, Inst Precis Med, Kaohsiung 804201, Taiwan
关键词
rheumatoid arthritis; cochleopathy; hearing impairment; neuropathy; ossicles; steroid; SENSORINEURAL HEARING-LOSS; MIDDLE-EAR INVOLVEMENT; TNF-ALPHA BLOCKERS; HYDROXYCHLOROQUINE OTOTOXICITY; SALICYLATE OTOTOXICITY; DISEASE-ACTIVITY; IMPAIRMENT; INFLIXIMAB; DEAFNESS; ADALIMUMAB;
D O I
10.3390/ijms252413290
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Hearing impairment in patients with rheumatoid arthritis has been underestimated for decades. Rheumatoid arthritis can affect both the middle ear (specifically, the incudomalleolar and incudostapedial joints) and inner ear (including the cochlea and acoustic nerve) simultaneously. Despite ongoing research, consensus on effective treatments for hearing impairment in these patients remains elusive. This systematic review aims to consolidate clinically relevant information for healthcare providers by summarizing current evidence on hearing impairment in rheumatoid arthritis patients. We conducted the current systematic review by searching platforms of PubMed, Embase, ClinicalKey, Web of Science, and ScienceDirect to retrieve eligible articles regarding hearing impairment related to rheumatoid arthritis. We extract any data on characteristics, pathophysiology, examination, and treatment related to rheumatoid arthritis. Based on the currently available evidence, we advocate for the use of specific audiometric tests to facilitate early detection of hearing impairment in these patients. Regular audiological assessments are recommended to monitor hearing ability and potentially prevent further deterioration. Finally, we propose a modified treatment protocol that integrates steroids, hydroxychloroquine, and non-invasive brain stimulation as a novel therapeutic approach for managing these symptoms. This protocol aims to offer clinicians new strategies to address hearing impairment in patients with rheumatoid arthritis effectively.
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页数:18
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