Climate change effects on the human gut microbiome: complex mechanisms and global inequities

被引:2
作者
Litchman, Elena [1 ,2 ]
机构
[1] Michigan State Univ, Kellogg Biol Stn, Hickory Corners, MI 49060 USA
[2] Michigan State Univ, Dept Integrat Biol, Hickory Corners, MI USA
基金
美国国家科学基金会;
关键词
FOOD; HEALTH; IMPACT; DIVERSITY; CO2; TEMPERATURE; NUTRITION; DIET; DYSBIOSIS; PATHOGEN;
D O I
10.1016/S2542-5196(24)00332-2
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Ongoing global climate change is affecting all aspects of life on Earth, including human health. The gut microbiota is an important determinant of health in humans and other organisms, but how climate change affects gut microbiota remains largely unexplored. In this Review, I discuss how the changing climate might affect gut microbiota by altering the quantity and quality of food, as well as environmental microbiomes, such as enteric pathogen pressure and host physiology. Climate change-induced variability in food supply, shifts in elemental and macromolecular composition of plant and animal food, the proliferation of enteric pathogens, and the direct effects of high temperatures on gut physiology might alter gut microbiota in undesirable ways, increasing the health burden of climate change. The importance of different pathways might depend on many geographical, economic, and ecological factors. Microbiomes of populations in low-income countries might be disproportionally affected through greater climate change effects and poor mitigation on diet, pathogen burden, and host physiology.
引用
收藏
页码:e134 / e144
页数:11
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