The protective effects and mechanism of myricetin in liver diseases (Review)

被引：1
作者：
Chen, Mi [1 ]
Zhang, Shengnan [1 ,2 ]
Huang, Xingqiong [1 ]
Zhang, Dandan [1 ]
Zhu, Dan [1 ]
Ouyang, Changhan [1 ]
Li, Yankun [1 ]
机构：
[1] Hubei Univ Sci & Technol, Sch Pharm, Hubei Key Lab Diabet & Angiopathy, 88 Xianning Ave, Xianning 437100, Hubei, Peoples R China
[2] Hubei Univ Sci & Technol, Sch Resources Environm Sci & Engn, Xianning 437100, Hubei, Peoples R China
来源：
MOLECULAR MEDICINE REPORTS | 2025年 / 31卷 / 04期
关键词：
acute liver injury; fatty liver; liver fibrosis; hepatocellular carcinoma; myricetin; GENE-EXPRESSION; APOPTOSIS; DAMAGE; P53; DNA;
D O I：
10.3892/mmr.2025.13452
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Liver diseases have become one of the significant threats to global health. However, there is a lack of effective targeted therapeutic drugs in this field and the existing drugs used for liver disease treatment usually have side-effects. Traditional Chinese medicine (TCM) has the distinctive advantages of multi-target and low side-effects. As a flavonoid with various pharmacological activities such as anti-tumour, anti-oxidant, anti-inflammatory and anti-bacterial, the TCM myricetin has been widely used in liver disease research. The present work focuses on the role and molecular mechanism of myricetin in liver diseases such as acute liver injury, fatty liver, liver fibrosis and hepatocellular carcinoma. It is a promising reference for further research and application of myricetin in the treatment of liver diseases.
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页数：9
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