Three new terpenoid derivatives from the deep-sea-derived fungus Aspergillus sydowii DFFSCS007

被引：0
|
作者：
Ren, Xu-Meng [1 ,2 ]
Wu, Ke-Yue [1 ,2 ]
Qi, Shu-Hua [1 ]
机构：
[1] Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med, Guangzhou 510301, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2024年
基金：
中国国家自然科学基金;
关键词：
Deep-sea-derived fungus; Aspergillus sydowii; terpenoid derivative; METABOLITES;
D O I：
10.1080/10286020.2024.2443086
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Three new terpenoid derivatives (1S,6R,7S)-hydrobenzosydowic acid (1), (1 R,6S,7S)-hydrobenzosydowic acid (2), and (7 R,10R)-11-dehydroxy-iso-10-hydroxysydowic acid (3), along with the known analogues (S)-2-(1-(4-nitrobenzoyl)pyrrolidine-2-carboxamido)benzoic acid (4) and trihydroxybutyl ester of 4-carboxydiorcinol (5) were isolated from the deep-sea-derived fungus Aspergillus sydowii DFFSCS007. Their structures were determined by spectroscopic analysis. Compound 4 with a nitrobenzene group was isolated from nature for the first time. The antibacterial activities of 1-5 and cytotoxicity of 1-3 were also evaluated. [GRAPHICS]
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页数：8
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