Silicocarnotite-A New Ceramic Material With Potential Application in Bone Tissue Regeneration

Silicocarnotite (Ca-5(PO4)(2)(SiO4)) is an inorganic crystalline material classified as a silicophosphate. Its chemical composition is similar to that of calcium hydroxyapatite (Ca-10(PO4)(6)(OH)(2)) and silicon-substituted hydroxyapatite (Ca-10(PO4)(6-x)(SiO4)(x)(OH)(2-x-square)). Given the critical role of silicon ions in bone tissue metabolism, mineralization, and collagen synthesis, silicon-enriched hydroxyapatites have long been of significant interest in regenerative medicine. The natural presence of silicate ions in the structure of silicophosphates has prompted research into their synthesis and potential application as bone substitute materials in reconstructive and reparative bone surgery. This article reviews the current state of knowledge on silicocarnotite, including its physicochemical and biological properties, the application potential, and prospective research directions.