This paper studies the sensing base station (SBS) that has great potential to improve the safety of vehicles and pedestrians on roads. SBS can detect the targets on the road with communication signals using the integrated sensing and communication (ISAC) technique. Compared with vehicle-mounted radar, SBS has a better sensing field due to its higher deployment position, which can help solve the problem of sensing blind areas. In this paper, key technologies of SBS are studied, including the beamforming algorithm, beam scanning scheme, and interference cancellation algorithm. To transmit and receive ISAC signals simultaneously, a double-coupling antenna array is applied. The free detection beam and directional communication beam are proposed for joint communication and sensing to meet the requirements of beamwidth and pointing directions. The joint time- space-frequency domain division multiple access algorithm is proposed to cancel the interference of SBS, including multiuser interference and duplex interference between sensing and communication. Finally, the sensing and communication performance of SBS under the industrial scientific medical power limitation is analyzed and simulated. Simulation results show that the communication rate of SBS can reach over 100 Mbps and the range of sensing and communication can reach about 500 m.