Palladium-Catalyzed Synthesis of Substituted Phenanthrenes via a C-H Annulation of 2-Biaryl Triflates with Alkynes

被引：0
作者：
Prabhakaran, Mohan [1 ]
Parthasarathy, Kanniyappan [1 ]
机构：
[1] Univ Madras, Dept Organ Chem, Chennai 600025, Tamil Nadu, India
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 89卷 / 22期
关键词：
POLYCYCLIC AROMATIC-HYDROCARBONS; 4+2 BENZANNULATION; SELECTIVE SYNTHESIS; CYTOTOXIC ACTIVITY; PI-EXTENSION; PHENANTHROINDOLIZIDINE; ALKALOIDS; DERIVATIVES; CHEMISTRY; INSERTION;
D O I：
10.1021/acs.joc.4c01369
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new palladium-catalyzed efficient method for the synthesis of substituted 9,10-phenanthrenes from 2-biaryl triflates with alkynes has been developed. This method provides a great opportunity to prepare various symmetrical and unsymmetrical phenanthrene derivatives in good yields. This reaction proceeds via C-OTf bond cleavage and alkyne insertion followed by C-H annulation.
引用
收藏
页码：16363 / 16374
页数：12
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