Current Japanese pharmaceutical chemistry

被引：0

作者：

Aoki, Kazumasa ^{[1
]}

Nagasawa, Hideko ^{[2
]}

机构：

[1] Daiichi Sankyo Co Ltd, R&D Div, Res Funct, Shinagawa R&D Ctr, 1-2-58 Hiromachi,Shinagawa Ku, Tokyo 1408710, Japan

[2] Gifu Pharmaceut Univ, Lab Pharmaceut & Med Chem, 1-25-4 Daigaku Nishi, Gifu 5011196, Japan

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 2025年 / 119卷

关键词：

D O I：

10.1016/j.bmc.2025.118068

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页数：3

共 41 条

[1] Design and synthesis of novel and potent allosteric HIV-1 integrase inhibitors with a spirocyclic moiety [J].

Adachi, Kaoru ;

Manabe, Tomoyuki ;

Yamasaki, Takayuki ;

Suma, Akira ;

Orita, Takuya ;

Furuzono, Tomoko ;

Adachi, Tsuyoshi ;

Ohata, Yoshitsugu ;

Akiyama, Yoshiyuki ;

Miyazaki, Susumu .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 110

[2] Molecular design and evaluation of aza-polycyclic carbamoyl pyridones as HIV-1 integrase strand transfer inhibitors [J].

Akiyama, Toshiyuki ;

Johns, Brian A. ;

Taoda, Yoshiyuki ;

Yoshida, Hiroshi ;

Taishi, Teruhiko ;

Kawasuji, Takashi ;

Murai, Hitoshi ;

Yoshinaga, Tomokazu ;

Sato, Akihiko ;

Seki, Takahiro ;

Koyama, Mikiko ;

Miki, Shigeru ;

Kawauchi-Miki, Shinobu ;

Kagitani-Suyama, Akemi ;

Fujiwara, Tamio .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 111

[3] Optimization of α-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 (β5i)/LMP2 β5i)/LMP2 (β1i) β 1i) dual inhibitor [J].

Arai, Yuuki ;

Shitama, Hiroaki ;

Yamagishi, Masahito ;

Ono, Satoshi ;

Kashima, Akiko ;

Hiraizumi, Masahiro ;

Tsuda, Naoki ;

Katayama, Koushirou ;

Tanaka, Kouji ;

Koda, Yuzo ;

Kato, Sayuka ;

Sakata, Kei ;

Nureki, Osamu ;

Miyazaki, Hiroshi .

BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 109

[4] Michael addition-activated alkylation of G-quadruplex DNA with methylamine-protected vinyl-quinazolinone derivatives [J].

Chen, Yutong ;

Onizuka, Kazumitsu ;

Nagatsugi, Fumi .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 109

[5] Cyano-Hydrol green derivatives: Expanding the 9-cyanopyronin-based resonance Raman vibrational palette [J].

Fujioka, Hiroyoshi ;

Murao, Yuta ;

Okinaka, Momoko ;

Spratt, Spencer John ;

Shou, Jingwen ;

Kawatani, Minoru ;

Kojima, Ryosuke ;

Tachibana, Ryo ;

Urano, Yasuteru ;

Ozeki, Yasuyuki ;

Kamiya, Mako .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 106

[6] Drug-drug conjugates of MEK and Akt inhibitors for RAS-mutant cancers [J].

Fujita, Hikaru ;

Arai, Sachiko ;

Arakawa, Hiroshi ;

Hamamoto, Kana ;

Kato, Toshiyuki ;

Arai, Tsubasa ;

Nitta, Nanaka ;

Hotta, Kazuki ;

Hosokawa, Natsuko ;

Ohbayashi, Takako ;

Takahashi, Chiaki ;

Inokuma, Yasuhide ;

Tamai, Ikumi ;

Yano, Seiji ;

Kunishima, Munetaka ;

Watanabe, Yoshihiro .

BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 102

[7] Discovery of DS44470011: An oral hypoxia-inducible factor prolyl hydroxylase inhibitor for the treatment of renal anemia [J].

Fukuda, Takeshi ;

Kuribayashi, Takeshi ;

Takano, Rieko ;

Sasaki, Koji ;

Tsuji, Takashi ;

Niitsu, Yoichi ;

Ishii, Ken ;

Hashimoto, Masami ;

Baba, Daichi ;

Ito, Shuichiro ;

Tanaka, Naoki .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 108

[8] Discovery of a potent, orally available furopyridine derivative as a novel selective bromodomain and extra-terminal domain (BET)-first bromodomain (BD1) inhibitor [J].

Hagihara, Shuichi ;

Ishizawa, Kouhei ;

Kikuchi, Manami ;

Kawano, Yuko ;

Nishidate, Akiko ;

Matsumoto, Fumi ;

Hashimoto, Naohiro ;

Sasaki, Chiduko ;

Miyaguchi, Ikuko ;

Okada, Okimasa ;

Akashi, Tomoya ;

Nakayama, Shinji ;

Ogasawara, Yuko ;

Endo, Junichi .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 109

[9] Discovery of a potent orally available pyrazolopyridone derivative as a novel selective bromodomain and extra-terminal domain (BET)-first bromodomain (BD1) inhibitor [J].

Hagihara, Shuichi ;

Ishizawa, Kouhei ;

Soga, Kana ;

Honjo, Takashi ;

Takai, Shigeki ;

Kawano, Yuko ;

Kikuchi, Manami ;

Nishidate, Akiko ;

Matsumoto, Fumi ;

Murase, Mikako ;

Hashimoto, Naohiro ;

Sasaki, Chiduko ;

Miyaguchi, Ikuko ;

Okada, Okimasa ;

Akashi, Tomoya ;

Nakayama, Shinji ;

Ogasawara, Yuko ;

Endo, Junichi .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 109

[10] α-Fluorination of tropane compounds and its impact on physicochemical and ADME properties [J].

Hoshikawa, Tamaki ;

Kurokawa, Toshiki ;

Yoshimura, Hikaru ;

Shibuguchi, Tomoyuki .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 108

← 1 2 3 4 5 →