Acute Kidney Injury after Cardiac Surgery

被引：3

作者：

Beaver, Thomas M. ^{[1
]}

Dass, Bhagwan ^{[2
,3
]}

Patel, Ami M. ^{[4
,5
]}

Ejaz, A. Ahsan ^{[4
,5
]}

机构：

[1] Univ Florida, Div Cardiovasc Surg, Gainesville, FL USA

[2] Carl Hyden VA Med Ctr, Sect Nephrol, Phoenix, AZ USA

[3] Univ Arizona, Div Nephrol, Phoenix, AZ USA

[4] Univ Maryland, Sch Med, Div Nephrol, Baltimore, MD 21201 USA

[5] VA Maryland Healthcare Syst, Baltimore, MD 21201 USA

来源：

CARDIORENAL MEDICINE | 2024年 / 14卷 / 01期

关键词：

Cardiac surgery; Acute kidney injury; ATRIAL-NATRIURETIC-PEPTIDE; ACUTE-RENAL-FAILURE; ALL-CAUSE MORTALITY; CARDIOPULMONARY BYPASS; RISK; DYSFUNCTION; PREVENTION; FUROSEMIDE; NESIRITIDE; DOPAMINE;

D O I：

10.1159/000540396

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Cardiac surgery-associated acute kidney injury (CS-AKI) remains a vexing issue. Clinical trials for the prevention of CS-AKI have been disappointing despite enormous initial enthusiasm based on experimental data. Summary: The schism in experimental and clinical data has triggered a relook at our understanding of CS-AKI and the experimental and preclinical models. In this review, we discuss the therapeutic targets of major clinical trials. Key Messages: The silver lining in the midst is the standardization of anesthetic and perioperative care proposed by national societies. Implementation of the KDIGO bundle is a reasonable option to decrease the incidence of CS-AKI despite lack of proven robust benefits. s (c) 2024 The Author(s). Published by S. Karger AG, Basel

引用

页码：437 / 442

页数：6

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