Acute Kidney Injury after Cardiac Surgery

被引：2
作者：
Beaver, Thomas M. [1 ]
Dass, Bhagwan [2 ,3 ]
Patel, Ami M. [4 ,5 ]
Ejaz, A. Ahsan [4 ,5 ]
机构：
[1] Univ Florida, Div Cardiovasc Surg, Gainesville, FL USA
[2] Carl Hyden VA Med Ctr, Sect Nephrol, Phoenix, AZ USA
[3] Univ Arizona, Div Nephrol, Phoenix, AZ USA
[4] Univ Maryland, Sch Med, Div Nephrol, Baltimore, MD 21201 USA
[5] VA Maryland Healthcare Syst, Baltimore, MD 21201 USA
来源：
CARDIORENAL MEDICINE | 2024年 / 14卷 / 01期
关键词：
Cardiac surgery; Acute kidney injury; ATRIAL-NATRIURETIC-PEPTIDE; ACUTE-RENAL-FAILURE; ALL-CAUSE MORTALITY; CARDIOPULMONARY BYPASS; RISK; DYSFUNCTION; PREVENTION; FUROSEMIDE; NESIRITIDE; DOPAMINE;
D O I：
10.1159/000540396
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Background: Cardiac surgery-associated acute kidney injury (CS-AKI) remains a vexing issue. Clinical trials for the prevention of CS-AKI have been disappointing despite enormous initial enthusiasm based on experimental data. Summary: The schism in experimental and clinical data has triggered a relook at our understanding of CS-AKI and the experimental and preclinical models. In this review, we discuss the therapeutic targets of major clinical trials. Key Messages: The silver lining in the midst is the standardization of anesthetic and perioperative care proposed by national societies. Implementation of the KDIGO bundle is a reasonable option to decrease the incidence of CS-AKI despite lack of proven robust benefits. s (c) 2024 The Author(s). Published by S. Karger AG, Basel
引用
收藏
页码：437 / 442
页数：6
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