Nanozymes as a novel solution for oxidative stress reduction and nitrogen compound removal in aquatic systems: a study on common carp (Cyprinus carpio) (Withdrawn Publication. See vol. 607, 2025)

被引：1

作者：

Tawfeeq, Ammar Abdulrazzaq ^{[1
,2
]}

Mohammed, Th. T. ^{[2
]}

Aldahham, Bilal J. M. ^{[1
]}

机构：

[1] Univ Anbar, Coll Appl Sci Hit, Anbar, Iraq

[2] Univ Anbar, Coll Agr, Anbar, Iraq

来源：

FISH PHYSIOLOGY AND BIOCHEMISTRY | 2025年 / 51卷 / 02期

关键词：

Nanozymes; CeO2; NPs; Fe3O4; Oxidative stress; Common carp; AMMONIA; WATER; RESPONSES; NANOPARTICLES; ANTIOXIDANT; TOXICITY; EXPOSURE; NITRATE; GROWTH; TIO2;

D O I：

10.1007/s10695-025-01491-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Antioxidants in fish are vital biomarkers when exposed to pollutants that cause oxidative stress. Among the most important components of the antioxidant defense system are the enzymes superoxide dismutase (SOD) and catalase (CAT). This study aimed to evaluate the potential of certain nanomaterials as nanozymes by mimicking the activity of SOD and CAT enzymes when added to the diet of common carp, simultaneously, removing the efficacy of nitrogen waste. To evaluate the effect of nanozymes on common carp fish, six types of experimental diets were used over 84 days. The study included six groups: a control group (T1) on a standard diet, and five groups supplemented with 1 mg kg(-)1 of potassium dichromate (K2Cr2O7). Among these, T3 and T4 also received 1 mg kg(-)1 and 5 mg kg(-)1 of CeO2 nanoparticles, respectively, while T5 and T6 were given 1 mg kg(-)1 and 5 mg kg(-)1 of Fe3O4 nanoparticles, respectively. The experiment aimed to study the effects of K2Cr2O7 combined with varying doses of CeO2 and Fe3O4 nanoparticles. The results of the current study indicated a significant reduction (P <= 0.05) in certain nitrogenous compounds (ammonia and nitrates) in water in nanozyme treatments. The study also demonstrated a significant improvement (P <= 0.05) in productive performance in (T6), a significant decrease (P <= 0.05) in liver enzyme activity in blood serum in (T3), and a significant increase (P <= 0.05) in glutathione peroxidase (GPx) enzyme activity in (T5). Furthermore, there was a significant increase (P <= 0.05) in the gene expression of the enzymes SOD and CAT in (T4), as well as the gene expression of the GPx enzyme in (T6). The current study concludes that CeO2 and Fe3O4 nanoparticles can be added to fish diets as nanozymes to combat oxidative stress in fish by mimicking the activities of the body's antioxidant enzymes. Nanozymes seem to reduce nitrogenous pollutants via adsorption or possibly oxidation.

引用

页数：16