Surgical and survival outcomes of cytoreductive surgery alone or with perioperative intraperitoneal chemotherapy in high peritoneal cancer index

被引：0

作者：

Ercan, Metin ^{[1
]}

Aziret, Mehmet ^{[2
]}

Karaman, Kerem ^{[2
]}

Kose, Osman ^{[3
]}

Oter, Volkan ^{[4
]}

Yirgin, Hakan ^{[2
]}

Kaya, Ahmet ^{[1
]}

Kahraman, Yavuz Selim ^{[1
]}

Kose, Elif ^{[5
]}

Bostanci, Erdal Birol ^{[4
]}

Unal, Orhan ^{[6
]}

机构：

[1] Sakarya Univ, Fac Med, Dept Surg Oncol, Sakarya, Turkiye

[2] Sakarya Univ, Fac Med, Dept Gastroenterol Surg, Sakarya, Turkiye

[3] Sakarya Univ, Fac Med, Dept Gynecol Oncol Surg, Sakarya, Turkiye

[4] Univ Hlth Sci, Ankara City Hosp, Clin Gastroenterol Surg, Ankara, Turkiye

[5] Sakarya Univ, Fac Med, Dept Publ Hlth, Sakarya, Turkiye

[6] Yeditepe Univ, Fac Med, Dept Gynecol Oncol Surg, Istanbul, Turkiye

来源：

TURKISH JOURNAL OF SURGERY | 2024年 / 40卷 / 03期

关键词：

Peritoneal metastases; peritoneal cancer index; cytoreductive surgery; early post-operative intraperitoneal chemotherapy; hyperthermic in- traperitoneal chemotherapy; COLORECTAL-CANCER; CURATIVE TREATMENT; OVARIAN-CANCER; CARCINOMATOSIS; HIPEC; ORIGIN; MANAGEMENT; MORBIDITY; COMPLICATIONS; MALIGNANCIES;

D O I：

暂无

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Objective: The aim of this study was to examine the early surgical and long-term survival outcomes of cytoreductive surgery (CRS) alone and CRS plus perioperative intraperitoneal chemotherapy (IPC) in patients with peritoneal metastases (PM). Material and Methods: CRS alone or CRS plus IPC was performed on 122 patients for various intraabdominal PMs. Patients were divided into two groups as PCI <= 19 and PCI >19 to compare early surgical outcomes. Results: Among PM patients 70 (57.4%) were of non-ovarian and 52 (42.6%) were of ovarian origin. Of the patients 74 (60.7%) were in the peritoneal cancer index (PCI) <= 19 group and 48 (39.3%) were in the PCI >19 group. The complication ratio of PCI >19 group was higher than that of the PCI <= 19 group and median overall survival (OS) of PCI >19 group was lower than that of the PCI <= 19 group. Complete or nearly complete (CCR-0/CCR-1) resections rates were similar in both groups (95.9% in the PCI <= 19 group and 93.8% in the PCI >19 group). However, CCR-0 resection rate was found to be lower in the PCI >19 group compared to the PCI <= 19 group (60.8% vs. 39.6%) (p< 0.001). Conclusion: CCR-0/CCR-1 resections can be achieved with CRS in most patients with PCI >19 score. It would be appropriate to consider CRS or CRS plus perioperative IPC for palliative purposes in selected patients with PCI >19 score.

引用

页码：219 / 228

页数：10

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