THE ANTI-INFLAMMATORY EFFECTS OF ASPIRIN IN THE TREATMENT OF GUM DISEASES

被引:0
作者
Topor, Gabi [1 ]
Huzum, Riana Maria [2 ]
Forna, Doriana Agop [2 ]
Maftei, Malina Iris [2 ]
Stefan, Simona Claudia [1 ,3 ]
机构
[1] Dunarea Jos Univ, Fac Med & Pharm, 35 Al I Cuza Str, Galati 800010, Romania
[2] Grigore T Popa Univ Med & Pharm, 16 Univ St, Iasi 700115, Romania
[3] Dunarea Jos Univ Galati, Ctr Res Med Pharmaceut Field, Galati, Romania
来源
ROMANIAN JOURNAL OF ORAL REHABILITATION | 2024年 / 16卷 / 03期
关键词
aspirin; NSAIDs; gum disease; periodontal treatment; topical formulations; efficacy and efficency; GINGIVAL CREVICULAR FLUID; ORTHODONTIC WIRES; CONVERSION; FREQUENCY; THERAPY; BUTANES; BUTENES; SYSTEMS;
D O I
10.6261/RJOR.2024.3.16.63
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
This study examines the use of aspirin in dentistry, focusing on the treatment of gingival and periodontal diseases. Aspirin, known for its anti-inflammatory, analgesic and anticoagulant properties, is widely used in medicine, but its application in dentistry requires a thorough understanding of the associated benefits and risks. The review discusses aspirin's mechanisms of action, its impact on periodontal health at the cellular and molecular level, and the potential for the development of topical formulations to minimize side effects. Current studies and the need for long-term research to evaluate the efficacy and safety of aspirin are also addressed. The paper identifies significant gaps in the existing literature, including the need to investigate drug interactions and tailor treatment to individual patient characteristics. In conclusion, aspirin has significant potential to improve the management of periodontal disease, but further investigation is needed to optimize the treatment protocol and ensure its safe use in dental practice.
引用
收藏
页码:616 / 628
页数:13
相关论文
共 50 条
[31]   Aspirin and non-steroidal anti-inflammatory drugs inhibit amyloid-β aggregation [J].
Thomas, T ;
Nadackal, TG ;
Thomas, K .
NEUROREPORT, 2001, 12 (15) :3263-3267
[32]   Nonsteroidal Anti-Inflammatory Drugs, Aspirin, and Cognitive Function in the Baltimore Longitudinal Study of Aging [J].
Waldstein, Shari R. ;
Wendell, Carrington Rice ;
Seliger, Stephen L. ;
Ferrucci, Luigi ;
Metter, E. Jeffrey ;
Zonderman, Alan B. .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2010, 58 (01) :38-43
[33]   Does aspirin or non-aspirin non-steroidal anti-inflammatory drug use prevent colorectal cancer in inflammatory bowel disease? [J].
Burr, Nick E. ;
Hull, Mark A. ;
Subramanian, Venkataraman .
WORLD JOURNAL OF GASTROENTEROLOGY, 2016, 22 (13) :3679-3686
[34]   Anti-inflammatory treatment in Kawasaki disease [J].
Carriere, JP ;
Chaix, Y ;
Grouteau, E .
MEDECINE ET MALADIES INFECTIEUSES, 1998, 28 :581-585
[35]   Anti-thrombotic and anti-inflammatory activity of sulodexide compared to aspirin in the rat model [J].
Sohn, Sung-Hwa ;
Kim, Tae Sik ;
Kim, Ji-Won ;
Yoo, Sung Mook ;
Jo, Won-Min .
CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 2021, 77 (04) :435-442
[36]   Nonsteroidal anti-inflammatory drugs for retinal neurodegenerative diseases [J].
Chen, Chen ;
Wang, Chenguang ;
Zhou, Xuebin ;
Xu, Lingxian ;
Chen, Han ;
Qian, Kun ;
Jia, Bo ;
Su, Guanfang ;
Fu, Jinling .
PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2021, 156
[37]   Aminosalicylates and aspirin for colonic cancer: From anti-inflammatory to antineoplastic drugs? [J].
Allgayer, H ;
Tillmann, T ;
Hombach, A ;
Kruis, W ;
Pohl, C .
ZEITSCHRIFT FUR GASTROENTEROLOGIE, 2000, 38 (12) :963-970
[38]   Intravenous aspirin challenge as a diagnosis of nonsteroidal anti-inflammatory drugs hypersensitivity [J].
Seong, Gil Myeong ;
Lee, Jaechun ;
Kim, Changhwan .
ASIAN PACIFIC JOURNAL OF ALLERGY AND IMMUNOLOGY, 2020, 38 (02) :124-128
[39]   Investigation into the Combination of Aspirin with Non-steroidal Anti-inflammatory Drugs [J].
Ito, Naoko ;
Yokoyama, Haruko ;
Soeda, Shinji ;
Suzuki, Yuji ;
Ikeda, Noriyuki ;
Tokuoka, Kentaro ;
Watanabe, Masayuki ;
Kitagawa, Yasuhisa ;
Yamada, Yasuhiko .
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2011, 131 (07) :1073-1077
[40]   Vestibular Schwannoma Growth With Aspirin and Other Nonsteroidal Anti-inflammatory Drugs [J].
Hunter, Jacob B. ;
O'Connell, Brendan P. ;
Wanna, George B. ;
Bennett, Marc L. ;
Rivas, Alejandro ;
Thompson, Reid C. ;
Haynes, David S. .
OTOLOGY & NEUROTOLOGY, 2017, 38 (08) :1158-1164