Potential of a phytotherapeutic emulgel composed of Stryphnodendron adstringens (Mart.) Coville and Copaifera martii for topical wound healing

Silva J & uacute;nior R.C., Pelissari K.P., Morais F.A.P., Scapim M.R.S., Valenciano F.G., Perez H.L., Bezerra R.A.D., Pozza M.S.S., Caetano W. & Campanholi K.S.S. 2024. Potential of a phytotherapeutic emulgel composed of Stryphnodendron adstringens (Mart.) Coville and Copaifera martii for topical wound healing. Pesquisa Veterin & aacute;ria Brasileira 44:e07354, 2024. Departamento de Quimica, N & uacute;cleo de Pesquisas em Sistemas Fotodin & acirc;micos e Nanomedicina, Universidade Estadual de Maring & aacute;, Av. Colombo 5790, Maring & aacute;, PR 87020900, Brazil. E-mail: katieli_souza@hotmail.com Myiasis is a worsening parasitic condition in newborn sheep, requiring effective medications for healing. This article demonstrates the development of a phytotherapeutic emulgel (phytogel) composed of copaiba oil ( Copaifera martii) and "barbatim & atilde;o" ( Stryphnodendron adstringens (Mart.) Coville) incorporated into a polymeric blend composed of Pluronic (R) F127 and Carbopol (R) 934P. The formulation demonstrated antimicrobial potential by inactivating the bacteria Staphylococcus aureus. Administering the phytotherapeutic to the umbilicus of newborn lambs for five days effectively promoted healing and prevented inflammation and myiasis. The erythrogram and leukogram of the animals showed statistical equivalence between the animals treated with the phytotherapeutic and iodine. Furthermore, the human intervention index of the phytogel was lower when compared to iodine. The results underscore the medication's potential, warranting further studies in veterinary medicine.