Photocatalytic Degradation of Ciprofloxacin: A Combined Experimental and Theoretical Study Using Curcumin and Hydrogen Peroxide

被引:0
作者
de Paiva, Florida L. P. [1 ]
Silva, Maria Vivian C. [1 ]
Mendonca, Ana Lara F. [1 ]
Araujo, Cristiane S. [1 ]
Sallum, Loide O. [2 ]
de Aguiar, Antonio S. N. [1 ]
Lima, Alessandra R. [3 ]
Napolitano, Hamilton B. [1 ,4 ]
Calvete, Mario J. F. [5 ]
Dias, Lucas D. [1 ]
机构
[1] Univ Evangel Goias, Lab Novos Mat, BR-75083515 Anapolis, GO, Brazil
[2] Univ Evangel Goias, Lab Ciencias Farmaceut, BR-75083515 Anapolis, GO, Brazil
[3] Univ Sao Paulo, Lab Biofoton Ambiental, Inst Fis Sao Carlos, BR-13560970 Sao Carlos, SP, Brazil
[4] Univ Estadual Goias, Grp Quim Teor & Estrutural Anapolis, BR-75083515 Anapolis, GO, Brazil
[5] Univ Coimbra, Ctr Quim Coimbra, Dept Quim, Rua Larga, P-3004535 Coimbra, Portugal
基金
巴西圣保罗研究基金会;
关键词
photodegradation; environment; antibiotic; ciprofloxacin; curcumin; hydrogen peroxide; molecular modeling; DENSITY; APPROXIMATION; EXCHANGE; STATES; WATER;
D O I
10.3390/separations11090260
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Contamination of soil, water, and wastewater by pharmaceuticals, including antibiotics, is a global health problem. This work evaluated the use of a natural compound, curcumin (CUR), as a homogeneous photocatalyst, together with hydrogen peroxide (H2O2) as a benign oxidant, to promote the photodegradation of ciprofloxacin (CIP). Furthermore, we carried out theoretical calculations using density functional theory (DFT) to assess the chemical reactivity of ciprofloxacin. In addition, the intermolecular interaction patterns of two crystalline polymorphs of the antibiotic drug were analyzed through Hirshfeld surfaces. Finally, calculations using the TD-DFT formalism were carried out to understand the effects on the CIP molecule caused by the simultaneous presence of the CUR molecule and ultraviolet-visible light (UV-Vis). A photooxidative effect was observed in the presence of the CUR photocatalyst (CIP + CUR (1:0.5)), resulting in a degradation of CIP of up to 24.4%. However, increasing the concentration of the CUR photocatalyst (ciprofloxacin + curcumin (1:1)) decreased the photodegradation of CIP, which may be caused by competition between the CIP molecule and CUR for ROS generated in situ. Additionally, the calculation results showed that the electronic excitations caused by the associated CIP + CUR structures affect the CIP molecule, resulting in the effects observed experimentally. The results show that CUR, when applied as a photosensitizing catalyst, presents synergistic potential with H2O2 in the photocatalytic degradation of ciprofloxacin. This photocatalytic process can be applied to the environmental remediation of pharmaceutical micropollutants, a subject of ongoing studies.
引用
收藏
页数:14
相关论文
共 50 条
  • [41] Effect of hydrogen peroxide on the photocatalytic degradation of methyl tert-butyl ether
    Zang, Yujing
    Farnood, Ramin
    TOPICS IN CATALYSIS, 2006, 37 (2-4) : 91 - 96
  • [42] DEGRADATION OF TOLUENE USING UV/HYDROGEN PEROXIDE PROCESS
    Cai, Shaokang
    Sun, Yue
    Gao, Canzhu
    Li, Pengfei
    Cheng, Zhongfa
    ENVIRONMENT PROTECTION ENGINEERING, 2021, 47 (01): : 5 - 15
  • [43] Photocatalytic degradation of parathion in aqueous TiO2 dispersion:: The effect of hydrogen peroxide and light intensity
    Chen, TF
    Doong, RA
    Lei, WG
    WATER SCIENCE AND TECHNOLOGY, 1998, 37 (08) : 187 - 194
  • [44] Intra- and intermolecular hydrogen bondings in steroids -: a combined experimental and theoretical study
    Magyar, A
    Szendi, Z
    Kiss, JT
    P linkó, I
    JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM, 2003, 666 : 163 - 168
  • [45] Enhancing the photocatalytic degradation of ciprofloxacin contaminant using a combined laser irradiation (285/365 nm) and porous g-C3N4
    Oliva, J.
    Sanchez, J.
    Romero Servin, S.
    Ruiz-Santoyo, J. A.
    Garcia, C. R.
    Vallejo, M. A.
    Alvarez-Valtierra, L.
    Gomez-Solis, C.
    MATERIALS CHEMISTRY AND PHYSICS, 2020, 252 (252)
  • [46] Polyoxometalates covalently combined with graphitic carbon nitride for photocatalytic hydrogen peroxide production
    Zhao, Shen
    Zhao, Xu
    Ouyang, Shuxin
    Zhu, Yongfa
    CATALYSIS SCIENCE & TECHNOLOGY, 2018, 8 (06) : 1686 - 1695
  • [47] Photocatalytic degradation of ciprofloxacin and sulfamethoxazole on a carbon nanodot doped tungsten trioxide: degradation product study
    Busisiwe Nokalika Zwane
    Nonhlangabezo Mabuba
    Benjamin O. Orimolade
    Babatunde A. Koiki
    Omotayo A. Arotiba
    Reaction Kinetics, Mechanisms and Catalysis, 2020, 131 : 453 - 470
  • [48] Photocatalytic ozonation degradation of ciprofloxacin using ZnO nanoparticles immobilized on the surface of stones
    Malakootian, Mohammad
    Mahdizadeh, Hakimeh
    Dehdarirad, Abbas
    Gharghani, Majid Amiri
    JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY, 2019, 40 (06) : 846 - 854
  • [49] Adsorption and photocatalytic degradation of 2,4-dichlorophenol in TiO2 suspensions. Effect of hydrogen peroxide, sodium peroxodisulphate and ozone
    Pulido Melian, E.
    Gonzalez Diaz, O.
    Dona Rodriguez, J. M.
    Arana, J.
    Perez Pena, J.
    APPLIED CATALYSIS A-GENERAL, 2013, 455 : 227 - 233
  • [50] Photocatalytic degradation of ciprofloxacin using semiconductor derived from heterostructured ZIF-8-based materials
    Santos, Wemerson D. C.
    Teixeira, Mayara M.
    Campos, Ingrid R.
    de Lima, Roberto B.
    Mantilla, Angeles
    Osajima, Josy A.
    de Menezes, Alan S.
    Manzani, Danilo
    Rojas, Alex
    Alcantara, Ana C. S.
    MICROPOROUS AND MESOPOROUS MATERIALS, 2023, 359