Estimation of the optimal treatment regimes with multiple treatments under proportional hazards model

被引:0
|
作者
Fang, Yuexin [1 ]
Tan, Xiangyong [2 ,4 ]
Li, Qian [3 ]
机构
[1] Shanghai Normal Univ, Dept Math, Shanghai, Peoples R China
[2] Jiangxi Univ Finance & Econ, Sch Stat & Data Sci, Nanchang, Peoples R China
[3] Nanjing Univ Posts & Telecommun, Sch Econ, Nanjing, Peoples R China
[4] Jiangxi Univ Finance & Econ, Key Lab Data Sci Finance & Econ, Nanchang, Peoples R China
基金
中国博士后科学基金; 中国国家自然科学基金;
关键词
Optimal treatment regimes; Time-to-event data; Multiple treatments; Doubly robust;
D O I
10.1016/j.spl.2025.110357
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
We propose a novel proportional hazards model that include an unknown baseline covariate effect and the interaction between multiple treatments and covariates on censored survival data. Doubly robust estimating equations constructed by utilizing the A-learning methodology and time-dependent propensity score. The asymptotic properties of the proposed estimators are established under the correct specification of either the baseline effect model or the propensity score model. Extensive simulation studies, along with an application, demonstrate the efficacy of the proposed approach.
引用
收藏
页数:7
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