Ocular invasion in sinonasal malignant melanoma: A case report and review of literature

被引:1
|
作者
Khademi, Bijan [1 ]
Soltani, Sajjad [1 ]
Yousefi, Alireza [1 ]
Heidari, Pouya [1 ]
Mardani, Zhale [2 ]
Yousufzai, Shayan [3 ]
机构
[1] Shiraz Univ Med Sci, Khalili Hosp, Head & Neck Surg Dept, Shiraz, Iran
[2] Shiraz Univ Med Sci, Sch Med, Dept Pathol, Shiraz, Iran
[3] Shiraz Univ Med Sci, Shiraz, Iran
来源
INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS | 2025年 / 127卷
关键词
Sinonasal mucosal melanoma; SNMM; Case report; Functional endoscopic sinus surgery; Prognosis; Adjuvant therapy; MUCOSAL MELANOMA; NASAL CAVITY; MANAGEMENT; OUTCOMES;
D O I
10.1016/j.ijscr.2025.110904
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Sinonasal mucosal melanoma (SNMM) is a rare and aggressive malignancy associated a poor prognosis, prognosis. It is by delayed presentation and nonspecific symptoms. The incidence of SNMM is low, with and there are challenges in achieving local control and managing distant metastases. Case Presentation. We report present case of an 86-year-old female patient with a history of systemic hypertension who presented exhibited symptoms, including blurred vision, rhinorrhea, and facial pain, following initial treatment for SNMM. sinonasal mucosal melanoma (SNMM). studies revealed a heterogeneous lesion in the right nasal cavity and ethmoidal air cells, exhibiting characterized by destruction and invasion into the orbit. The patient underwent functional endoscopic sinus surgery (FESS) for resection, with and analysis confirming confirmed the diagnosis of melanoma. Discussion: This case underscores the aggressive nature of SNMM and emphasizes importance of early diagnosis and intervention. Despite Although treatment with surgery and radiotherapy leading resulted in resolution for two years, the recurrence of symptoms highlights the challenges in associated with long-term control. The Effective of SNMM requires necessitates multidisciplinary approach, approach that includes resection and the of adjuvant therapies. Conclusion: SNMM poses presents treatment challenges due to its aggressive behavior nature complex anatomical location. A comprehensive approach involving that includes radiotherapy, and potential systemic therapies is essential for improving enhancing outcomes. Further research is needed necessary explore investigate treatment strategies for this rare malignancy.
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页数:6
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