Recent advances in Tetraphenylethylene-based aggregation-induced electrochemiluminescence for biosensing applications

被引：4
作者：
Dong, Zhiyong [1 ,2 ]
Du, Fangxin [3 ]
Zhang, Wei [1 ,2 ]
Tian, Yu [1 ,2 ]
Xu, Guobao [1 ,2 ]
机构：
[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Jilin, Peoples R China
[2] Univ Sci & Technol China, Sch Appl Chem & Engn, Hefei 230026, Peoples R China
[3] Huaibei Normal Univ, Sch Chem & Mat Sci, Huaibei 235000, Peoples R China
来源：
CURRENT OPINION IN ELECTROCHEMISTRY | 2025年 / 49卷
基金：
中国国家自然科学基金;
关键词：
Tetraphenylethylene; Aggregation-induced electrochemiluminescence; Biosensing; Near-infrared electrochemiluminescence; Immunosensor; METAL-ORGANIC FRAMEWORK; POLYMER DOTS;
D O I：
10.1016/j.coelec.2024.101627
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Tetraphenylethylene (TPE), a prominent aggregation-induced emission (AIE) emitter, has gained significant attention in the development of electrochemiluminescence (ECL) biosensors due to its unique luminescent properties. The combination of AIE and ECL improves the ECL intensity and efficiency, making TPE-based systems ideal for high-sensitivity AIECL biosensing applications. This review discusses recent advances in TPE and its derivatives based small molecular materials (e.g., nanoaggregates, organic dots, silica and vesicles confined TPE-based materials) and polymers (e.g., polymer dots, metal-organic frameworks and covalent organic frameworks) for biological applications. The AIECL principles of TPE-based materials are explored, which are mainly through molecular aggregation, spatial confinement and rigid structure to restrict the motions of TPE and reduce non-radiative transitions to realize high ECL emission. Finally, current challenges are addressed, along with perspectives on future directions to improve the performance and expand the applicability of TPE-based AIECL platforms in bioanalysis.
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页数：9
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共 51 条
[1]   Aggregation-Induced Electrochemiluminescence of Platinum(II) Complexes [J].
Carrara, Serena ;
Aliprandi, Alessandro ;
Hogan, Conor F. ;
De Cola, Luisa .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2017, 139 (41) :14605-14610
[2]   Solvent Regulation Induced Cathode Aggregation-Induced Electrochemiluminescence of Tetraphenylethylene Nanoaggregates for Ultrasensitive Zearalenone Analysis [J].
Chen, Jiao-Jie ;
Pan, Meng-Qi ;
Cao, Wei-Wei ;
Wang, Zhen ;
Yuan, Ruo ;
Wang, Hai-Jun .
ANALYTICAL CHEMISTRY, 2024, 96 (22) :9043-9050
[3]   Aggregation-induced emission: fundamental understanding and future developments [J].
Chen, Yuncong ;
Lam, Jacky W. Y. ;
Kwok, Ryan T. K. ;
Liu, Bin ;
Tang, Ben Zhong .
MATERIALS HORIZONS, 2019, 6 (03) :428-433
[4]   Ultrasensitive Ratiometric Electrochemiluminescence Sensor with an Efficient Antifouling and Antibacterial Interface of PSBMA@SiO2-MXene for Oxytetracycline Trace Detection in the Marine Environment [J].
Ding, Mengli ;
Zhang, Shulei ;
Wang, Jinge ;
Ding, Yan ;
Ding, Caifeng .
ANALYTICAL CHEMISTRY, 2023, 95 (44) :16327-16334
[5]   Luminol electrochemiluminescence by combining cathodic reduction and anodic oxidation at regenerable cobalt phthalocyanine modified carbon paste electrode for dopamine detection [J].
Dong, Zhiyong ;
Du, Fangxin ;
Barkae, Tesfaye Hailemariam ;
Ji, Kaixiang ;
Liu, Fangshuo ;
Snizhko, Dmytro ;
Guan, Yiran ;
Xu, Guobao .
ELECTROCHIMICA ACTA, 2023, 441
[6]   Single-Electrode Electrochemical System for the Visual and High-Throughput Electrochemiluminescence Immunoassay [J].
Du, Fangxin ;
Dong, Zhiyong ;
Guan, Yiran ;
Zeid, Abdallah M. ;
Ma, Di ;
Feng, Jiachun ;
Yang, Di ;
Xu, Guobao .
ANALYTICAL CHEMISTRY, 2022, 94 (04) :2189-2194
[7]   Framework-Induced Electrochemiluminescence Enhancement of an AIEgen-Based MOF Coupled with Heterostructured TiO2@Ag NPs as an Efficient Coreaction Accelerator for Sensitive Biosensing [J].
Du, Yu ;
Li, Faying ;
Ren, Xiang ;
Wu, Dan ;
Ma, Hongmin ;
Kuang, Xuan ;
Li, Jingshuai ;
Feng, Rui ;
Wei, Qin .
ANALYTICAL CHEMISTRY, 2024, 96 (37) :14926-14934
[8]   Synthesis of silica-encapsulated tetraphenylethylene with aggregation-induced electrochemiluminescence resonance energy transfer for sensitively sensing microcystin-LR [J].
Du, Yu ;
Jiang, Su ;
Han, Yun ;
Liu, Qian ;
Cui, Lin ;
Zhang, Chun -yang .
TALANTA, 2024, 272
[9]   Facile fabrication of silica nanoparticles with incorporation of AIEgen and coreactant as self-enhanced electrochemiluminescence probes for sensitive immunoassay of microcystin-LR [J].
Du, Yu ;
Jiang, Su ;
Yuan, Hui-min ;
Cui, Lin ;
Zhang, Chun-yang .
SENSORS AND ACTUATORS B-CHEMICAL, 2024, 401
[10]   Boosting Electrochemiluminescence Immunoassay Sensitivity via Co-Pt Nanoparticles within a Ti3C2 MXene-Modified Single Electrode Electrochemical System on Raspberry Pi [J].
Firoozbakhtian, Ali ;
Hosseini, Morteza ;
Guan, Yiran ;
Xu, Guobao .
ANALYTICAL CHEMISTRY, 2023, 95 (40) :15110-15117
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