Delayed Normal Pressure Hydrocephalus after Deep Brain Stimulation in Parkinson's Disease

被引:0
作者
Kola, Sruthi [1 ]
Karri, Madhavi [1 ]
Sehrish, Sumaiya [2 ]
Fathima, Syed Tazeem [1 ]
Mohareer, Sindhuja [1 ]
Prasad, Vanakuru Venkata Siva Rama Krishna [1 ]
Kandadai, Rukmini Mridula [1 ]
Alugolu, Rajesh [1 ]
Varma, Ravi [2 ]
Borgohain, Rupam [1 ]
机构
[1] Parkinsons Dis & Movement Disorders Res Ctr, Hyderabad, India
[2] Citi Neuro Ctr, Dept Neuroradiol, Hyderabad, India
关键词
deep brain stimulation; dystonia; normal pressure hydrocephalus; Parkinson's disease;
D O I
10.1002/mdc3.70022
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background: Deep brain stimulation (DBS) of the bilateral subthalamic nuclei (STN) or globus pallidus internus (GPi) for Parkinson's disease (PD) and dystonia is known for its efficacy despite potential complications. Although acute complications such as intracranial hemorrhage and infections are documented, delayed occurrences like normal pressure hydrocephalus (NPH) post-DBS has not been reported so far. Cases: We present a case series of seven PD patients (from 974) who developed NPH, an average of 10.9 + 3.1 years after DBS (6 STN, 1 GPi) with symptoms of cognitive decline and gait disturbances. Imaging confirmed hydrocephalus meeting NPH criteria (Radscale >4), which was further confirmed by the cerebrospinal fluid tap trial. Treatment with ventriculoperitoneal shunt placement showed significant symptom improvement. Conclusion: Recognizing NPH in PD patients even after DBS is crucial for early intervention and improved outcomes.
引用
收藏
页码:681 / 686
页数:6
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