Ultra-high Versus Standard Resolution Photon-Counting Detector CT Angiography for Imaging of Femoral Stents in a Cadaveric Perfusion Model

被引：1

作者：

Hartung, Viktor ^{[1
]}

Hendel, Robin ^{[1
]}

Huflage, Henner ^{[1
]}

Augustin, Anne Marie ^{[1
,5
]}

Grunz, Jan-Peter ^{[1
,4
]}

Kleefeldt, Florian ^{[2
]}

Peter, Dominik ^{[3
]}

Lichthardt, Sven ^{[3
]}

Erguen, Sueleyman ^{[2
]}

Bley, Thorsten Alexander ^{[1
]}

Gruschwitz, Philipp ^{[1
]}

机构：

[1] Univ Hosp Wurzburg, Dept Diagnost & Intervent Radiol, Wurzburg, Germany

[2] Univ Wurzburg, Inst Anat & Cell Biol, Wurzburg, Germany

[3] Univ Hosp Wurzburg, Ctr Operat Med, Dept Gen Visceral Transplant Vasc & Pediat Surg, Wurzburg, Germany

[4] Univ Wisconsin, Dept Radiol, Madison, WI USA

[5] Klinikum Bayreuth, Dept Intervent & Diagnost Radiol, Bayreuth, Germany

来源：

ACADEMIC RADIOLOGY | 2025年 / 32卷 / 01期

关键词：

Photon-counting CT; Ultra-high resolution; Peripheral arterial runoff; Image quality; Peripheral arterial disease;

D O I：

10.1016/j.acra.2024.07.038

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Background and Aims: The aim of this study was to investigate the imaging performance and quality differences of PCD-CT in standard resolution mode (SR) versus ultra-high resolution mode (UHR) in the lower extremity runoff of dose-matched CTAs in a human cadaveric model. Methods: Extracorporeal perfusion of the upper leg was established in one fresh-frozen human cadaver via inguinal and popliteal accesses using a peristaltic pump. Seven peripheral stents were deployed in the SFA. Photon-counting CTAs were performed under contrast perfusion in SR and UHR mode with dose-equivalent 120 kVp acquisition protocols (low-/ medium-/ high-dose: CTDIVol = 3, 5, 10 mGy) and reconstructed with four vascular convolution kernels. Lumen visibility and contrast-to-noise ratio were compared using analyses of variance. Subjective image quality was assessed using a pairwise, forced-choice comparison software. Results: Lumen visibility was equal for SR and UHR at the used dose levels. CNR increase by UHR was significant for (ultra-)sharp convolution kernels BV60 (3 mGy; UHR vs. SR, 19.9 +/- 1.9 vs. 15.7 +/- 1.6, p < 0.046) and BV76 (8.0 +/- 0.6 vs. 5.4 +/- 0.3, p < 0.001). The relative CNR increase was higher for low-dose than high-dose scans (BV76: 48% vs. 36% at high dose, p < 0.033). The CNR of the low-dose scan in UHR mode was comparable to the high-dose scan in SR mode when the ultra-sharp kernel was used (8.0 +/- 0.6 vs. 9.1 +/- 1.1, p > 0.760). Among UHR examinations, a significant increase in CNR could only be measured in BV76 (8.0 +/- 0.6 (3 mGy) vs. 12.4 +/- 0.9 (10 mGy), p < 0.001). Readers preferred subjective image quality of UHR for all kernels with BV76 being ranked highest. Conclusion: The CNR increase in UHR mode is highest when combining low radiation dose and ultra-sharp reconstructions. Meanwhile, the subjective image quality in UHR mode generally supersedes SR images, suggesting further dose reduction potential.

引用

页码：556 / 564

页数：9

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