COVID-19 Vaccines Effectiveness and Safety in Trinidad and Tobago: A Systematic Review and Meta-Analysis

被引：0

作者：

Justiz-Vaillant, Angel ^{[1
]}

Roopnarine, Kimberly ^{[1
]}

Solomon, Shaundell ^{[1
]}

Phillips, Alyssa ^{[1
]}

Sandy, Solange ^{[1
]}

Subero, Alyssa ^{[1
]}

Seepersad, Sarah ^{[1
]}

Span, Nicholas ^{[1
]}

Ramnath, Phalmanie ^{[1
]}

Ramnarine, Akaasha ^{[1
]}

Ramdath, Bimala ^{[1
]}

Rampaul, Chelsea ^{[1
]}

Ramdial, Renissa ^{[1
]}

Phagoo, Dana ^{[1
]}

Ramdhanie, Thalia ^{[1
]}

Moonilal, Vinaya ^{[1
]}

Poliah, Emily-Marie ^{[1
]}

Poonwassie, Steffan ^{[1
]}

Punilal, Karishta ^{[1
]}

Panchoo, Sarah ^{[1
]}

Parris, Justice ^{[1
]}

Oudit, Steven ^{[1
]}

Muir, Trudy ^{[1
]}

Nicholas-Joseph, Johnson ^{[1
]}

Pandit, Bijey Raj ^{[1
]}

Pakeerah, Sanjeev ^{[1
]}

Sookoo, Vesham ^{[1
]}

Richards, Patrice ^{[1
]}

John, Tishia ^{[1
]}

Gopaul, Darren ^{[2
]}

Soodeen, Sachin ^{[1
]}

Arozarena-Barbosa, Odette ^{[3
]}

Williams, Arlene ^{[1
]}

Unakal, Chandrashehkar ^{[1
]}

Fundora, Rodolfo Arozarena ^{[3
,4
]}

Thompson, Reinand ^{[1
]}

Akpaka, Patrick Eberechi ^{[1
]}

机构：

[1] Univ West Indies, Dept Para Clin Sci, St Augustine Campus, St Augustine 330912, Trinidad Tobago

[2] Morehouse Sch Med, Dept Surg, Atlanta, GA 30310 USA

[3] Eric Williams Med Sci Complex, North Cent Reg Hlth Author, Champs Fleurs 330912, Trinidad Tobago

[4] Univ West Indies, Fac Med Sci, Dept Clin & Surg Sci, St Augustine 330912, Trinidad Tobago

来源：

MICROORGANISMS | 2025年 / 13卷 / 01期

关键词：

Pfizer-BioNTech; modern; Novavax; AstraZeneca; Sinopharm; Janssen; vaccine effectiveness (VE); COVID-19; Trinidad and Tobago; MYOCARDITIS; ACCEPTANCE; EFFICACY;

D O I：

10.3390/microorganisms13010135

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This systematic review evaluated the effectiveness and side effects of various COVID-19 vaccines, with a focus on Trinidad and Tobago. The Pfizer-BioNTech and Moderna vaccines demonstrated the highest efficacy, particularly against COVID-19 variants, while Janssen and Sinopharm were comparatively less effective. mRNA vaccines, such as Pfizer-BioNTech and Oxford-AstraZeneca, were associated with more frequent and severe side effects, including soreness, fever, and cardiovascular issues. The review also identified significant gaps in the current scientific literature regarding COVID-19 vaccination issues in Trinidad and Tobago. These gaps highlight the need for comprehensive research to address vaccination challenges, including public health communication, equitable access, and local perceptions of vaccine safety. This analysis provides a foundation for developing targeted strategies to improve vaccine effectiveness in the region.

引用

页数：61

共 109 条

[1] Cardiac MRI in patients with COVID-19 infection
Abdeldayem, Emad H.
Mosaad, Basant M. Raief M.
Yassin, Aya
Abdelrahman, Ahmed S.
[J]. EUROPEAN RADIOLOGY, 2023, 33 (06) : 3867 - 3877
[2] Side effects of Pfizer/BioNTech (BNT162b2) COVID-19 vaccine reported by the Birzeit University community
Abukhalil, Abdallah Damin
Shatat, Sireen Sultan
Abushehadeh, Raya Riyad
Al-Shami, Ni'meh
Naseef, Hani A.
Rabba, Abdullah
[J]. BMC INFECTIOUS DISEASES, 2023, 23 (01)
[3] Immune thrombocytopenia associated with Pfizer-BioNTech's BNT162b2 mRNA COVID-19 vaccine
Akiyama, Hiroaki
Kakiuchi, Seiji
Rikitake, Junpei
Matsuba, Hiroyuki
Sekinada, Daisuke
Kozuki, Yoko
Iwata, Nobuko
[J]. IDCASES, 2021, 25
[4] Pfizer-BioNTech and Sinopharm: A Comparative Study on Post-Vaccination Antibody Titers
Alqassieh, Rami
Suleiman, Aiman
Abu-Halaweh, Sami
Santarisi, Abeer
Shatnawi, Omar
Shdaifat, Lara
Tarifi, Amjed
Al-Tamimi, Mohammad
Al-Shudifat, Abdel-Ellah
Alsmadi, Heba
Al Sharqawi, Ahmed
Alnawaiseh, Hadeel
Anasweh, Yara
Domaidah, Farah Abo
Abu Jaber, Haneen
Al-Zarir, Mohammad Rashid
Bsisu, Isam
[J]. VACCINES, 2021, 9 (11)
[5] Andrews N, 2022, NEW ENGL J MED, V386, P1532, DOI [10.1016/S1473-3099(22)00309-7, 10.1056/NEJMoa2119451]
[6] [Anonymous], 2023, COVID-19 Fortnightly Update
[7] [Anonymous], 2022, The Oxford Vaccine Trial
[8] Immunogenicity and safety of AZD1222 (ChAdOx1 nCoV-19) against SARS-CoV-2 in Japan: a double-blind, randomized controlled phase 1/2 trial
Asano, Michiko
Okada, Hiroshi
Itoh, Yohji
Hirata, Hajime
Ishikawa, Kensuke
Yoshida, Erika
Matsui, Akiko
Kelly, Elizabeth J.
Shoemaker, Kathryn
Olsson, Urban
Vekemans, Johan
[J]. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2022, 114 : 165 - 174
[9] Protection of BNT162b2 Vaccine Booster against Covid-19 in Israel
Bar-On, Yinon M.
Goldberg, Yair
Mandel, Micha
Bodenheimer, Omri
Freedman, Laurence
Kalkstein, Nir
Mizrahi, Barak
Alroy-Preis, Sharon
Ash, Nachman
Milo, Ron
Huppert, Amit
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2021, 385 (15) : 1393 - 1400
[10] Effectiveness of the Pfizer-BioNTech and Oxford-AstraZeneca vaccines on covid-19 related symptoms, hospital admissions, and mortality in older adults in England: test negative case-control study
Bernal, Jamie Lopez
Andrews, Nick
Gower, Charlotte
Robertson, Chris
Stowe, Julia
Tessier, Elise
Simmons, Ruth
Cottrell, Simon
Roberts, Richard
O'Doherty, Mark
Brown, Kevin
Cameron, Claire
Stockton, Diane
McMenamin, Jim
Ramsay, Mary
[J]. BMJ-BRITISH MEDICAL JOURNAL, 2021, 373

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