An overview of the microbiota of the oral cavity of humans and non-human primates with periodontal disease: Current issues and perspectives

被引：0
作者：
Miranda, Bruno Pires [1 ]
da Silva, Amanda Figueira [2 ]
Ascencao, Julia de Castro [3 ]
Santos, Helena Lucia Carneiro [4 ]
机构：
[1] Oswaldo Cruz Inst, Progress Trop Med, Dent Oral Biol & Pathol, Rio De Janeiro, Brazil
[2] Oswaldo Cruz Inst, Trop Med, Progress Trop Med, Rio De Janeiro, Brazil
[3] Oswaldo Cruz Inst, Biomed, Rio De Janeiro, Brazil
[4] Oswaldo Cruz Inst, Pathol, Sci Microbiol, Rio De Janeiro, Brazil
来源：
ARCHIVES OF ORAL BIOLOGY | 2025年 / 172卷
关键词：
Microbiota; Oral cavity; Periodontal disease; Humans; Primates; SUBGINGIVAL MICROBIOTA; GINGIVALIS;
D O I：
10.1016/j.archoralbio.2024.106121
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Objective: To provide a comprehensive summary of the available evidence on the oral microbiota of humans and non-human primates about the etiology of periodontal disease. Design: An integrative literature review was conducted on 398 clinical and observational articles published between 2010 and 2024 using searches in the MEDLINE/PubMed, Virtual Health Library, and SciELO databases. After the screening, eligibility, data extraction, and methodological quality assessment, 21 studies were selected. Results: The results, which reveal striking similarities between the pathogens involved in periodontal disease in humans and NHPs, confirm the potential of NHPs as research models and inspire further research in this area. Conclusion: According to these studies, Actinomyces spp., Aggregatibacter actinomycetemcomitans, Campylobacter rectus, Capnocytophaga spp., Eubacterium spp., Filifactor alocis, Fusobacterium spp., Leptotrichia spp., Neisseria mucosa, Parvimonas micra, Porphyromonas spp., Prevotella spp., Selenomonas spp., Streptococcus spp., Treponema spp., Tannerella spp., Veillonella parvula, were the genus and/or species of bacteria found in humans. On the other hand, Aggregatibacter acinomycetemcomitans, Campylobacter rectus, Desulfobulbus spp., Dialister invisus, Eikenella corrodens, Filifactor alocis, Fusobacterium spp., Parvimonas micra, Porphyromonas spp., Prevotella spp., Staphylococcus spp., Streptococcus spp., Treponema spp., Tannerella spp., Veillonella spp., were the most reported in NHPs. No study in non-human primates reported the presence of protozoa, unlike studies in humans that reported the presence of Entamoeba gingivalis and Trichomonas tenax. However, its role in periodontal disease still needs to be elucidated, despite the strong association mainly with severe periodontal disease where protozoa are observed in injured tissues.
引用
收藏
页数：9
相关论文
共 48 条
  • [1] Arweiler N.B., Netuschil L., The oral microbiota, Microbiota of the human body: Implications in health and disease, Chap. 4, pp. 45-60, (2016)
  • [2] Bao X., Wiehe R., Dommisch H., Schaefer A.S., Entamoeba gingivalis causes oral inflammation and tissue destruction, Journal of Dental Research, 99, 5, pp. 561-567, (2020)
  • [3] Benabdelkader S., Andreani J., Gillet A., Terrer E., Pignoly M., Chaudet H., Aboudharam G., La Scola B., Specific clones of Trichomonas tenax are associated with periodontitis, PloS One, 14, 3, (2019)
  • [4] Bisson C., Lec P.H., Blique M., Thilly N., Machouart M., Presence of trichomonads in subgingival biofilm of patients with periodontitis: Preliminary results, Parasitology Research, 117, 12, pp. 3767-3774, (2018)
  • [5] Bliss-Moreau E., Amara R.R., Buffalo E.A., Colman R.J., Embers M.E., Morrison J.H., Quillen E.E., Sacha J.B., Roberts C.T., National Primate Research Center Consortium Rigor and Reproducibility Working Group, Improving rigor and reproducibility in nonhuman primate research, American Journal of Primatology, 83, 12, (2021)
  • [6] Bonner M., Amard V., Bar-Pinatel C., Charpentier F., Chatard J.M., Desmuyck Y., Ihler S., Rochet J.P., Roux de la Tribouille V., Saladin L., Verdy M., Girones N., Fresno M., Santi-Rocca J., Detection of the amoeba Entamoeba gingivalis in periodontal pockets, Parasite, 21, (2014)
  • [7] Bostanci N., Belibasakis G.N., Porphyromonas gingivalis: An invasive and evasive opportunistic oral pathogen, FEMS Microbiology Letters, 333, 1, pp. 1-9, (2012)
  • [8] Bracamonte-Wolf C., Orrego P.R., Munoz C., Herrera D., Bravo J., Gonzalez J., Varela H., Catalan A., Araya J.E., Observational cross-sectional study of Trichomonas tenax in patients with periodontal disease attending a Chilean university dental clinic, BMC Oral Health, 19, 1, (2019)
  • [9] Chen Z., Yeoh Y.K., Hui M., Wong P.Y., Chan M.C.W., Ip M., Yu J., Burk R.D., Chan F.K.L., Chan P.K.S., Diversity of macaque microbiota compared to the human counterparts, Scientific Reports, 8, 1, (2018)
  • [10] Colombo A.P.V., Paster B.J., Grimaldi G., Lourenco T.G.B., Teva A., Campos-Neto A., McCluskey J., Kleanthous H., Van Dyke T.E., Stashenko P., Clinical and microbiological parameters of naturally occurring periodontitis in the non-human primate Macaca mulatta, Journal of Oral Microbiology, 9, 1, (2017)
12345