Coexistence of Intestinal Spirochetosis and Colorectal Cancer: Could the Coil be Carcinogenic?

被引：0

作者：

Zuercher, Hannah ^{[1
]}

Daneshmand, Arvin ^{[1
]}

Stolow, Eugene ^{[2
]}

Giansiracusa, Matthew ^{[1
]}

Allan, Robert ^{[3
]}

Sapounas, Antonios ^{[2
]}

机构：

[1] Univ Florida, Coll Med, Div Internal Med, Gainesville, FL 32610 USA

[2] Univ Florida, Div Gastroenterol Hepatol & Nutr, North Florida South Georgia Vet Hlth Syst, Coll Med, Gainesville, FL USA

[3] Univ Florida, Dept Pathol Immunol & Lab Med, Pathol & Lab Med Serv, North Florida South Georgia Vet Hlth Syst,Coll Me, Gainesville, FL USA

来源：

ACG CASE REPORTS JOURNAL | 2024年 / 11卷 / 11期

关键词：

intestinal spirochetosis; colorectal cancer; <italic>Brachyspira</italic>;

D O I：

10.14309/crj.0000000000001557

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Intestinal spirochetosis (IS) is an infectious gastrointestinal disease caused by Brachyspira bacteria. We detail an exceedingly rare case of IS with concomitant invasive colorectal adenocarcinoma (CRC) in a 58-year-old man presenting with abdominal discomfort and fever. Colonoscopic evaluation revealed abnormal-appearing, nodular cecal mucosa and a 35 mm rectosigmoid mass. Histopathology confirmed IS infection and CRC. Our case report is the first to detail IS diagnosed concurrently with colorectal cancer. It highlights the necessity of a high index of suspicion for IS in patients presenting with abdominal discomfort and endoscopic evidence of irregular nodular mucosa, particularly in the setting of suspected CRC. It further details potential pathophysiologic links between IS and colorectal malignancy.

引用

页数：4

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