Development of an electrochemical sensor for the detection of paracetamol using graphitic carbon nitride and single-walled carbon nanotubes

We present an electrochemical sensor for detecting paracetamol (PCT), based on a composite material created by thermally processing single-walled carbon nanotubes (SWCNTs) and graphitic carbon nitride (g-C3N4). The gC3N4/SWCNT nanocomposite was thoroughly characterized using UV-Vis spectroscopy, FT-IR, HR-SEM, HRTEM, Raman spectroscopy, and EDAX, confirming the successful synthesis of the composite. Electrochemical performance was assessed via cyclic voltammetry in a 0.1 M phosphate-buffered solution (PBS), demonstrating significantly enhanced current responses compared to the individual components. The electrochemical sensor exhibited excellent stability over 50 cycles and a notable increase in current response during the oxidation of 200 mu M paracetamol, highlighting its high sensitivity and selectivity. The g-C3N4/SWCNT nanocompositemodified electrode showed a linear detection range from 20 to 200 mu M, with a detection limit of 0.76 mu M. Therefore, this g-C3N4/SWCNT nanocomposite-coated electrode holds promise for detecting paracetamol in various biological and environmental samples.