A community-based study for evaluation of Ayurvedic formulations in the management of Osteoarthritis Knee

被引:0
作者
Mata, Sunita [1 ]
Makhija, Deepa [1 ]
Manathottathil, Aparna [1 ]
Rana, Rakesh Kumar [1 ]
Singh, Anukampa [1 ]
Tripathi, Arunabh [1 ]
Baheti, Sandip [2 ]
Srivastava, Alok Kumar [3 ]
Kumar, Amit [4 ]
Prasad, A. J. V. Sai [5 ]
Namburi, U. R. Sekhar [6 ]
Ghuse, Rahul [8 ]
Sharma, Gopesh [9 ]
Vyas, Kavita [10 ]
Dave, Parth [11 ]
Kumar, K. S. Praveen [7 ]
Singh, Neelam
Bharati, P. L. [7 ]
Kumar, Sanjiv [2 ]
Namdev, Kamble Pallavi [3 ]
Babu, Shyam [4 ]
Mohan, Midhuna [5 ]
Reddy, R. G. [6 ]
Shinde, Prashant
Sahu, S. K. [8 ]
Shah, Aaditya [9 ]
Antony, Chris [10 ]
Namburi, Sekhar
Paikrao, Summed [11 ]
Sharma, Abha [1 ]
Joshi, Vandana [1 ]
Rao, Bhogavalli Chandrasekhara [1 ]
Srikanth, Narayanam [1 ]
Acharya, Rabinarayan [1 ]
机构
[1] Cent Council Res Ayurved Sci CCRAS, D Block,Janakpuri Inst Area, Janakpuri, New Delhi, India
[2] Cent Ayurveda Res Inst, Patiala, Punjab, India
[3] Reg Ayurveda Res Inst, Uttar Pradesh India, Lucknow, India
[4] Reg Ayurveda Res Inst, Gwalior, Madhya Pradesh, India
[5] Reg Ayurveda Res Inst, Vijayawada, Andhra Prades, India
[6] Reg Ayurveda Res Inst, Nagpur, Maharashtra, India
[7] Cent Ayurveda Res Inst, Gauhati, India
[8] Reg Ayurveda Res Inst, Gangtok, Sikkim, India
[9] Reg Ayurveda Res Inst, Jammu, Jammu & Kashmir, India
[10] Reg Ayurveda Res Inst, Mandi, Himachal Prades, India
[11] Reg Ayurveda Res Inst, Ahmadabad, Gujarat, India
关键词
Osteoarthritis; Sandhigata Vata; Yograj Guggulu; Ashwagandha Churna; Narayana Taila; ASHWAGANDHA;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Background: Osteoarthritis (OA) of the knee is a major public health concern that leads to pain, disability and decreased quality of life. A similar condition has been described in Ayurveda under the name Sandhigata Vata which is caused by vitiation of Vata in the body. Objectives: Evaluation of the effectiveness and tolerability of Yograj Guggulu, Ashwagandha Churna, and Narayana Taila in OA knee. Materials and methods: The study was a prospective, multi-center, non-controlled interventional, community-based study conducted in 10 centres in India. 493 participants of any gender aged between 40 to 65 years & diagnosed with OA knee as per the diagnostic criteria American College of Rheumatology (2012), were enrolled in the study considering selection criteria. Ayurvedic formulations, Yograj Guggulu & Ashwagandha Churna were administered orally along with the local application of Narayana Taila twice daily for 12 weeks. The assessment was carried out on 28th, 56th, 84th and 112th day for any changes in the outcome measures. Results: The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total score, the WOMAC sub-scores for pain, stiffness and difficulty in physical activity, the Visual Analogue Scale (VAS) score for pain and the disease-specific symptoms were significantly decreased throughout treatment and during follow-up without intervention. Conclusion: The study demonstrates that the Ayurvedic interventions are well tolerable and beneficial in reducing the symptoms of OA knee.
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页码:1029 / 1036
页数:8
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