Squamous cell carcinoma in solid organ transplant recipients: Review of the literature

被引：0
作者：
Rius, Ines Oteiza [1 ]
Vicente, Ana Morello [1 ]
Gil, Leyre Aguado [1 ]
机构：
[1] Clin Univ Navarra, Dept Dermatol, Pamplona, Spain
来源：
MEDICINA CLINICA | 2024年 / 163卷 / 11期
关键词：
Squamous cell carcinoma; Solid organ transplant recipients; Immunosuppression; SKIN-CANCER CHEMOPREVENTION; FIELD CANCERIZATION; RISK; NICOTINAMIDE; PREVENTION; THERAPY; MANAGEMENT; INHIBITOR; RETINOIDS; EFFICACY;
D O I：
10.1016/j.medcli.2024.05.005
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Solid organ transplant recipients (SOTRs) exhibit an elevated incidence and aggressiveness of squamous cell carcinomas (SCCs) due to their immunosuppression. These tumors are associated with a heightened risk of metastasis and increased mortality. Therefore, an appropriate management of these patients is essential to improve their prognosis. Given the scarcity of studies on non-melanoma skin cancers (NMSCs) in SOTRs, this article aims to summarize and analyze the evidence gathered to date regarding therapeutic approaches, personalized monitoring, and prevention strategies for SCCs in these patients. Additionally, recent advancements in understanding SCCs within this patient group are also documented. (c) 2024 Elsevier Espana, S.L.U. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
引用
收藏
页码：570 / 576
页数：7
相关论文
共 60 条
[1]   Checkpoint inhibitor therapy for cancer in solid organ transplantation recipients: an institutional experience and a systematic review of the literature [J].
Abdel-Wahab, Noha ;
Safa, Houssein ;
Abudayyeh, Ala ;
Johnson, Daniel H. ;
Van Anh Trinh ;
Zobniw, Chrystia M. ;
Lin, Heather ;
Wong, Michael K. ;
Abdelrahim, Maen ;
Gaber, A. Osama ;
Suarez-Almazor, Maria E. ;
Diab, Adi .
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7
[2]   Immune Checkpoint Inhibitors and the Risk of Allograft Rejection: A Comprehensive Analysis on an Emerging Issue [J].
Aguirre, Luis E. ;
Guzman, Maria E. ;
Lopes, Gilberto ;
Hurley, Judith .
ONCOLOGIST, 2019, 24 (03) :394-401
[3]   Nicotinamide for Skin-Cancer Chemoprevention in Transplant Recipients [J].
Allen, Nicholas C. ;
Martin, Andrew J. ;
Snaidr, Victoria A. ;
Eggins, Renee ;
Chong, Alvin H. ;
Fernandez-Penas, Pablo ;
Gin, Douglas ;
Sidhu, Shireen ;
Paddon, Vanessa L. ;
Banney, Leith A. ;
Lim, Adrian ;
Upjohn, Edward ;
Schaider, Helmut ;
Ganhewa, Aparna D. ;
Nguyen, Jennifer ;
McKenzie, Catriona A. ;
Prakash, Saurabh ;
McLean, Catriona ;
Lochhead, Alistair ;
Ibbetson, Jan ;
Dettrick, Andrew ;
Landgren, Anthony ;
Allnutt, Katherine J. ;
Allison, Clare ;
Davenport, Rachael B. ;
Mumford, Blake P. ;
Wong, Brittany ;
Stagg, Brendan ;
Tedman, Alexander ;
Gribbin, Hannah ;
Edwards, Harrison A. ;
De Rosa, Nicholas ;
Stewart, Thomas ;
Doolan, Brent J. ;
Kok, Yonatan ;
Simpson, Kate ;
Low, Zhi M. ;
Kovitwanichkanont, Tom ;
Scolyer, Richard A. ;
Dhillon, Haryana M. ;
Vardy, Janette L. ;
Chadban, Steven J. ;
Bowen, David G. ;
Chen, Andrew C. ;
Damian, Diona L. .
NEW ENGLAND JOURNAL OF MEDICINE, 2023, 388 (09) :804-812
[4]   A long-term cohort study of acitretin for prevention of keratinocyte carcinoma in solid organ transplant recipients [J].
Allnutt, Katherine J. ;
Vogrin, Sara ;
Li, Jane ;
Goh, Michelle S. ;
Brennand, Sarah ;
Davenport, Rachael ;
Chong, Alvin H. .
AUSTRALASIAN JOURNAL OF DERMATOLOGY, 2022, 63 (02) :E121-E126
[5]   Incidence of Malignancies in Patients Treated With Sirolimus Following Heart Transplantation [J].
Asleh, Rabea ;
Clavell, Alfredo L. ;
Pereira, Naveen L. ;
Smith, Byron ;
Briasoulis, Alexandros ;
Alnsasra, Hilmi ;
Kremers, Walter K. ;
Habermann, Thomas M. ;
Otley, Clark C. ;
Li, Xin ;
Edwards, Brooks S. ;
Stulak, John M. ;
Daly, Richard C. ;
Kushwaha, Sudhir S. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2019, 73 (21) :2676-2688
[6]   Skin cancer in organ transplant recipients: Epidemiology, pathogenesis, and management [J].
Berg, D ;
Otley, CC .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2002, 47 (01) :1-17
[7]   Daylight photodynamic therapy for prevention of new actinic keratosis and keratinocyte carcinomas in organ transplants. A cryotherapy-controlled randomized clinical trial [J].
Bernad, I. ;
Aguado, L. ;
Nunez-Cordoba, J. M. ;
Redondo, P. .
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2020, 34 (07) :1464-1470
[8]   Research gaps in the management and prevention of cutaneous squamous cell carcinoma in organ transplant recipients [J].
Blomberg, M. ;
He, S. Y. ;
Harwood, C. ;
Arron, S. T. ;
Demehri, S. ;
Green, A. ;
Asgari, M. M. .
BRITISH JOURNAL OF DERMATOLOGY, 2017, 177 (05) :1225-1233
[9]   CD8+ Immunosenescence Predicts Post-Transplant Cutaneous Squamous Cell Carcinoma in High-Risk Patients [J].
Bottomley, Matthew J. ;
Harden, Paul N. ;
Wood, Kathryn J. .
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2016, 27 (05) :1505-1515
[10]   Free Cartilage Grafts for Alar Defects Coupled with Secondary-Intention Healing [J].
Campbell, Tracy ;
Eisen, Daniel B. .
DERMATOLOGIC SURGERY, 2011, 37 (04) :510-513
123456