Why N,N-dimethyltryptamine matters: unique features and therapeutic potential beyond classical psychedelics

被引：1
作者：
Chaves, Cristiano [1 ]
dos Santos, Rafael G. [2 ,3 ]
Dursun, Serdar M. [3 ,4 ,5 ]
Tusconi, Massimo [6 ]
Carta, Mauro Giovanni [7 ]
Brietzke, Elisa [1 ]
Hallak, Jaime E. C. [2 ,3 ,4 ,5 ]
机构：
[1] Queens Univ, Kingston Hlth Sci Ctr KHSC, Sch Med, Dept Psychiat, Kingston, ON, Canada
[2] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Neurosci & Behav, Sao Paulo, Brazil
[3] CNPq, Natl Inst Translat Med INCT TM, Sao Paulo, Brazil
[4] Univ Alberta, Dept Psychiat Neurochem Res Unit, Edmonton, AB, Canada
[5] Univ Alberta, Neurosci & Mental Hlth Inst, Edmonton, AB, Canada
[6] Univ Hosp Cagliari, Cagliari, Italy
[7] Univ Cagliari, Dept Med Sci & Publ Hlth, Cagliari, Italy
来源：
FRONTIERS IN PSYCHIATRY | 2024年 / 15卷
关键词：
dimethyltryptamine (DMT); ayahuasca; psychedelics; hallucinogen; neuroplasticity; sigma-1; receptor; serotonin 2A (5HT2A) receptor; pharmacology; LYSERGIC-ACID DIETHYLAMIDE; CROSS-TOLERANCE; SEROTONIN; 5-HT2A; AYAHUASCA; RECEPTOR; DIMETHYLTRYPTAMINE; MESCALINE; LSD-25; RAT; CONSCIOUSNESS;
D O I：
10.3389/fpsyt.2024.1485337
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
引用
收藏
页数：8
相关论文
共 112 条
  • [1] LYSERGIC-ACID DIETHYLAMIDE (LSD-25) - .17. TOLERANCE DEVELOPMENT AND ITS RELATIONSHIP TO A THEORY OF PSYCHOSIS
    ABRAMSON, HA
    JARVIK, ME
    GORIN, MH
    HIRSCH, MW
    [J]. JOURNAL OF PSYCHOLOGY, 1956, 41 (01) : 81 - 105
  • [2] PRODUCTION OF CROSS-TOLERANCE TO PSYCHOSIS-PRODUCING DOSES OF LYSERGIC-ACID DIETHYLAMIDE AND PSILOCYBIN
    ABRAMSON, HA
    ROLO, A
    SKLAROFSKY, B
    STACHE, J
    [J]. JOURNAL OF PSYCHOLOGY, 1960, 49 (01) : 151 - 154
  • [3] Potential therapeutic effects of an ayahuasca-inspired N,N-DMT and harmine formulation: a controlled trial in healthy subjects
    Aicher, Helena D.
    Mueller, Michael J.
    Dornbierer, Dario A.
    Suay, Dila
    Elsner, Claudius
    Wicki, Ilhui
    Meling, Daniel
    Caflisch, Luzia
    Hempe, Alexandra
    Steinhart, Camilla
    Mueller, Jovin
    Von Rotz, Robin
    Kleim, Birgit
    Scheidegger, Milan
    [J]. FRONTIERS IN PSYCHIATRY, 2024, 14
  • [4] TOLERANCE AND CROSS-TOLERANCE AMONG PSYCHOTOMIMETIC DRUGS
    APPEL, JB
    FREEDMAN, DX
    [J]. PSYCHOPHARMACOLOGIA, 1968, 13 (03): : 267 - &
  • [5] Exploring ayahuasca-assisted therapy for addiction: A qualitative analysis of preliminary findings among an Indigenous community in Canada
    Argento, Elena
    Capler, Rielle
    Thomas, Gerald
    Lucas, Philippe
    Tupper, Kenneth W.
    [J]. DRUG AND ALCOHOL REVIEW, 2019, 38 (07) : 781 - 789
  • [6] ENZYMATIC FORMATION OF PSYCHOTOMIMETIC METABOLITES FROM NORMALLY OCCURRING COMPOUNDS
    AXELROD, J
    [J]. SCIENCE, 1961, 134 (347) : 343 - &
  • [7] BALESTRIERI A, 1959, ARCH GEN PSYCHIAT, V1, P279
  • [8] Barker S A, 1981, Int Rev Neurobiol, V22, P83, DOI 10.1016/S0074-7742(08)60291-3
  • [9] Barker SA, 2022, PSYCHOPHARMACOLOGY, V239, P1749, DOI 10.1007/s00213-022-06065-0
  • [10] A critical review of reports of endogenous psychedelic N, N-dimethyltryptamines in humans: 1955-2010
    Barker, Steven A.
    McIlhenny, Ethan H.
    Strassman, Rick
    [J]. DRUG TESTING AND ANALYSIS, 2012, 4 (7-8) : 617 - 635
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