Association between tooth loss and geriatric syndromes in older adults: a cohort study from a rural area in eastern China

被引：0
作者：
Caihong He [1 ]
Yihan Wang [1 ]
Chengfan Qin [1 ]
Nan Hua [1 ]
Yichen Yang [1 ]
Jing Chen [1 ]
Qin Zhang [2 ]
机构：
[1] Department of Geriatrics, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou
[2] Key Laboratory of Diagnosis and Treatment of Aging and Physic-Chemical Injury Diseases of Zhejiang Province, The First Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, Hangzhou
[3] The First Affiliated Hospital of Zhejiang University School of Medicine, 79 Qingchun Road, Zhejiang Province, Hangzhou
来源：
Aging Clinical and Experimental Research | / 37卷 / 1期
关键词：
Falls; Frailty; Geriatric syndromes; Malnutrition risk; Sarcopenia; Tooth loss;
D O I：
10.1007/s40520-025-03032-5
中图分类号：
学科分类号：
摘要：
Background: Tooth loss was linked to health status, with substantial implications for malnutrition and chronic inflammation risks in older adults, especially among vulnerable groups. This study aimed to explore the associations between tooth loss severity, denture status, and geriatric syndromes. Methods: In 2019, 1094 participants were recruited and subjected to face-to-face interview to assess tooth loss severity, along with grip strength and body composition. In 2023, a follow-up was conducted with a subsample of the participants. Logistic regression analysis was utilized to explore the association between tooth loss severity at baseline and geriatric syndromes (sarcopenia, malnutrition risk, frailty, fall) at fourth year follow-up, as well as association between denture status and geriatric syndromes. Results: The multivariate analyses showed that having tooth loss affecting daily life at baseline was associated with a 1.80-fold higher prevalence of sarcopenia and 2.31-fold higher prevalence of malnutrition risk after four years. Participants with fewer than 10 teeth had significantly higher odds of geriatric syndromes compared to those with 21 or more teeth: 1.87-fold for sarcopenia (95% CI: 1.07 to 3.26), 2.99-fold for malnutrition risk (95% CI: 1.93 to 4.62), and 1.68-fold for frailty (95% CI: 1.10 to 2.56). Older adults with tooth loss who did not have dentures exhibited a significantly higher odds of sarcopenia, malnutrition risk, frailty, and falls, more number of geriatric syndromes. Conclusion: Higher severity level of tooth loss at baseline were associated with higher odds of geriatric syndromes at fourth year in older adults. Dentures partially mitigate the association between tooth loss and the higher odds of geriatric syndromes. Screening and intervening oral health is important for the prevention of geriatric syndromes in older adults. Clinical trial number: Not applicable. © The Author(s) 2025.
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