A current summary of coumarin-based compounds and their therapeutic applications

被引:0
作者
Mohamed, Fatma A. M. [1 ]
机构
[1] Jouf Univ, Coll Appl Med Sci Al Qurayyat, Dept Clin Lab Sci, Al Qurayyat 77454, Saudi Arabia
来源
EGYPTIAN JOURNAL OF CHEMISTRY | 2024年 / 67卷 / 13期
关键词
Coumarin; Cancer; Anti-inflammatory; Diabetic; Antioxidant; CA; BIOLOGICAL EVALUATION; PHARMACOLOGICAL EVALUATION; IN-VITRO; DESIGN; DERIVATIVES; INHIBITORS; WARFARIN; DOCKING; PHARMACOKINETICS; PHARMACOGENETICS;
D O I
10.21608/ejchem.2024.322591.10478
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Because of their importance in pharmacy and medicine, compounds with coumarin backbones are a particularly significant category of chemicals. Because of their conjugated double ring system, coumarins are intriguing molecules for a variety of research fields. Coumarins are used in industry as cosmetics and perfume ingredients, food additives, and most notably in the pharmaceutical industry to synthesize a wide range of synthetic pharmaceutical products. Coumarin derivatives' properties and biological activities play an important role in drug development. Coumarins have received increased interest from the scientific community in recent years due to their vast spectrum of biological activities, mostly due to their capacity to interact with numerous enzymes and receptors in living organisms. Numerous research articles and reviews contain information on this important family of compounds. In this review article, we attempt to keep the reader up to date on recent advances in coumarin biological activity, which may serve as a step-in drug design.
引用
收藏
页码:1417 / 1437
页数:21
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