Choosing Wisely: Effectiveness and Safety of Antibiotic Prophylaxis in Close Contacts of Invasive Group A Streptococci Infection

被引：0
|
作者：
Birck, Marina G. [1 ,2 ]
Moura, Cristiano S. [1 ]
Winthrop, Kevin L. [3 ]
Machado, Marina A. A. [1 ]
Neville, Autumn [1 ]
Bernatsky, Sasha [1 ,2 ]
机构：
[1] McGill Univ, Ctr Outcomes Res & Evaluat, Res Inst, Ctr Hlth, 5252 Boul Maisonneuve Ouest,3F-51, Montreal, PQ H4A 3S5, Canada
[2] McGill Univ, Dept Med, Montreal, PQ, Canada
[3] Oregon Hlth & Sci Univ, Div Infect Dis, Portland, OR USA
来源：
CLINICAL INFECTIOUS DISEASES | 2024年
基金：
加拿大健康研究院;
关键词：
streptococcal infections; antibiotic prophylactics; drug safety; comparative effectiveness research; healthcare administrative claims; UNITED-STATES; EPIDEMIOLOGY;
D O I：
10.1093/cid/ciae524
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Antibiotic prophylaxis is often recommended for close contacts of index cases of invasive Streptococcus pyogenes infections. Using MarketScan data (2010-2019), we found no difference in infection rates between those who received and those who did not receive antibiotics but a 3-fold increased risk of adverse events in those who did receive antibiotics.
引用
收藏
页码：314 / 315
页数：2
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