Implementation of modified enhanced recovery after surgery (ERAS) following surgery for abdominal trauma; Assessment of feasibility and outcomes: A randomized controlled trial (RCT)
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作者:
Jain, Vibhu
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Post Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, IndiaPost Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, India
Jain, Vibhu
[1
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Irrinki, Santhosh
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Post Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, IndiaPost Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, India
Irrinki, Santhosh
[1
]
Khare, Siddhant
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Post Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, IndiaPost Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, India
Khare, Siddhant
[1
]
Kurdia, Kailash Chand
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Post Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, IndiaPost Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, India
Kurdia, Kailash Chand
[1
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Nagaraj, Sathish Subbiah
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Post Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, IndiaPost Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, India
Nagaraj, Sathish Subbiah
[1
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Sakaray, Yashwant Raj
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Post Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, IndiaPost Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, India
Sakaray, Yashwant Raj
[1
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Savlania, Ajay
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Post Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, IndiaPost Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, India
Savlania, Ajay
[1
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Tandup, Cherring
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Post Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, IndiaPost Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, India
Tandup, Cherring
[1
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Verma, Prerna
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Post Grad Inst Med Educ & Res, Dept Anesthesia, Sect 12, Chandigarh 160012, IndiaPost Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, India
Verma, Prerna
[2
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Kaman, Lileshwar
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Post Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, IndiaPost Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, India
Kaman, Lileshwar
[1
]
机构:
[1] Post Grad Inst Med Educ & Res, Dept Gen Surg, Sect 12, Chandigarh 160012, India
[2] Post Grad Inst Med Educ & Res, Dept Anesthesia, Sect 12, Chandigarh 160012, India
Enhanced recovery after surgery;
ERAS;
Trauma;
Laparotomy;
Modified ERAS;
CARE;
D O I:
10.1016/j.amjsurg.2024.115975
中图分类号:
R61 [外科手术学];
学科分类号:
摘要:
Background: Enhanced recovery after surgery(ERAS) is a set of multiple perioperative care component not a rigid protocol with improved outcomes for elective surgeries. This study aimed to assess the feasibility and outcomes in trauma patients undergoing laparotomy. Study design:Prospective single-centre randomized controlled trial(RCT). Patients undergoing emergency laparotomy following trauma were randomized into ERAS(early removal of catheters, early mobilization and initiation of diet, use of opioid-sparing multimodal analgesia) and conventional care groups 24 h post-surgery. Outcome measures included length of hospitalization(LOH), recovery of bowel function, duration of removal of catheters and 30-day complications(Clavien-Dindo). Results: Fifty patients were randomized into ERAS(n = 25) and conventional care(n = 25) groups. Ninety-two percent of patients were young males, 58 % had blunt trauma to the abdomen and the most common indication of surgery was hollow viscus injury(88 %). ERAS group had a reduced median LOH(days) (6 versus 8, p = 0.007), early recovery of bowel function(p = 0.010) and shorter times for nasogastric tube(p = 0.001), urinary catheter(p = 0.007) and drain(p = 0.006) removal. The complications were comparable in both groups except for deep surgical site infection[significantly lower in ERAS group(p = 0.009)]. Conclusion: ERAS is safe and significantly reduces LOH in select trauma patients undergoing laparotomy.
机构:
Mayo Clin, Sch Grad Med Educ, Dept Obstet & Gynecol, Coll Med & Sci, Rochester, MN USAMayo Clin, Sch Grad Med Educ, Dept Obstet & Gynecol, Coll Med & Sci, Rochester, MN USA
Baker, Mary V.
Teles Abrao Trad, Ayssa
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Mayo Clin, Sch Grad Med Educ, Dept Obstet & Gynecol, Coll Med & Sci, Rochester, MN USAMayo Clin, Sch Grad Med Educ, Dept Obstet & Gynecol, Coll Med & Sci, Rochester, MN USA
Teles Abrao Trad, Ayssa
Tamhane, Prajakta
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机构:
Reid Hlth, Dept Family Med, Richmond, IN USAMayo Clin, Sch Grad Med Educ, Dept Obstet & Gynecol, Coll Med & Sci, Rochester, MN USA
Tamhane, Prajakta
Weaver, Amy L.
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机构:
Mayo Clin, Dept Quantitat Hlth Sci, Rochester, MN USAMayo Clin, Sch Grad Med Educ, Dept Obstet & Gynecol, Coll Med & Sci, Rochester, MN USA
Weaver, Amy L.
Visscher, Sue L.
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Mayo Clin, Robert D & Patricia E Kern Ctr Sci Hlth Care Deliv, Rochester, MN USAMayo Clin, Sch Grad Med Educ, Dept Obstet & Gynecol, Coll Med & Sci, Rochester, MN USA
Visscher, Sue L.
Borah, Bijan J.
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Mayo Clin, Dept Quantitat Hlth Sci, Rochester, MN USA
Mayo Clin, Robert D & Patricia E Kern Ctr Sci Hlth Care Deliv, Rochester, MN USA
Mayo Clin, Dept Obstet & Gynecol, Rochester, MN USAMayo Clin, Sch Grad Med Educ, Dept Obstet & Gynecol, Coll Med & Sci, Rochester, MN USA
Borah, Bijan J.
Klingele, Christopher J.
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Olmsted Med Ctr, Obstet & Gynecol, Rochester, MN USAMayo Clin, Sch Grad Med Educ, Dept Obstet & Gynecol, Coll Med & Sci, Rochester, MN USA
Klingele, Christopher J.
Gebhart, John B.
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Mayo Clin, Dept Obstet & Gynecol, Rochester, MN USAMayo Clin, Sch Grad Med Educ, Dept Obstet & Gynecol, Coll Med & Sci, Rochester, MN USA
Gebhart, John B.
Trabuco, Emanuel C.
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机构:
Mayo Clin, Dept Obstet & Gynecol, Rochester, MN USA
Dept Obstet & Gynecol, Mayo Clin, 200 First St SW, Rochester, MN 55905 USAMayo Clin, Sch Grad Med Educ, Dept Obstet & Gynecol, Coll Med & Sci, Rochester, MN USA
机构:
Sichuan Univ, West China Hosp, Dept Dermatovenereol, Chengdu 610041, Sichuan, Peoples R ChinaSichuan Univ, West China Hosp, Dept Dermatovenereol, Chengdu 610041, Sichuan, Peoples R China
Li, Jingyi
Zhu, Haibei
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机构:
Singapore Gen Hosp, Div Anaesthesiol & Perioperat Med, Outram Rd, Singapore 169608, SingaporeSichuan Univ, West China Hosp, Dept Dermatovenereol, Chengdu 610041, Sichuan, Peoples R China
Zhu, Haibei
Liao, Ren
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机构:
Sichuan Univ, West China Hosp, Dept Anesthesiol, 37 Guoxue Lane, Chengdu 610041, Sichuan, Peoples R ChinaSichuan Univ, West China Hosp, Dept Dermatovenereol, Chengdu 610041, Sichuan, Peoples R China
机构:
Inkosi Albert Luthuli Cent Hosp, Dept Surg, Durban, South Africa
Univ KwaZulu Natal, Dept Surg, Private Bag 7 Congella, ZA-4013 Durban, South AfricaInkosi Albert Luthuli Cent Hosp, Dept Surg, Durban, South Africa
Loots, Emil
Sartorius, Benn
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Univ KwaZulu Natal, Discipline Publ Hlth Med, Durban, South AfricaInkosi Albert Luthuli Cent Hosp, Dept Surg, Durban, South Africa
Sartorius, Benn
Paruk, Imran M.
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机构:
Univ KwaZulu Natal, Dept Diabet & Endocrinol, Durban, South AfricaInkosi Albert Luthuli Cent Hosp, Dept Surg, Durban, South Africa
Paruk, Imran M.
Clarke, Damian L.
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Univ KwaZulu Natal, Dept Surg, Private Bag 7 Congella, ZA-4013 Durban, South Africa
Greys Hosp, Dept Gen Surg, Pietermaritzburg, South AfricaInkosi Albert Luthuli Cent Hosp, Dept Surg, Durban, South Africa
机构:
Univ Toronto, Temerty Fac Med, Div Pediat Gen & Thorac Surg, Toronto, ON, Canada
Brigham & Womens Hosp, Harvard TH Chan Sch Publ Hlth, Ariadne Labs, Boston, MA USA
555 Univ Ave,1526 Hill Wing, Toronto, ON M5G 1X8, CanadaUniv Toronto, Temerty Fac Med, Div Pediat Gen & Thorac Surg, Toronto, ON, Canada
Pilkington, Mercedes
Pentz, Brandon
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Univ Calgary, Dept Surg, Calgary, AB, CanadaUniv Toronto, Temerty Fac Med, Div Pediat Gen & Thorac Surg, Toronto, ON, Canada
Pentz, Brandon
Lam, Jennifer Y. K.
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Western Univ, Schulich Sch Med & Dent, Div Pediat Surg, London, ON, CanadaUniv Toronto, Temerty Fac Med, Div Pediat Gen & Thorac Surg, Toronto, ON, Canada
Lam, Jennifer Y. K.
Stephen, Lori
论文数: 0引用数: 0
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机构:
Univ Calgary, Calgary, AB, CanadaUniv Toronto, Temerty Fac Med, Div Pediat Gen & Thorac Surg, Toronto, ON, Canada
Stephen, Lori
Howlett, Alexandra
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h-index: 0
机构:
Univ Calgary, Cumming Sch Med, Dept Pediat Neonatol, Calgary, AB, CanadaUniv Toronto, Temerty Fac Med, Div Pediat Gen & Thorac Surg, Toronto, ON, Canada
Howlett, Alexandra
Theam, Michelle
论文数: 0引用数: 0
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机构:
Univ Calgary, Cumming Sch Med, Dept Anesthesia, Calgary, AB, CanadaUniv Toronto, Temerty Fac Med, Div Pediat Gen & Thorac Surg, Toronto, ON, Canada
Theam, Michelle
Unrau, Jennifer
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Univ Calgary, Cumming Sch Med, Dept Pediat Neonatol, Calgary, AB, CanadaUniv Toronto, Temerty Fac Med, Div Pediat Gen & Thorac Surg, Toronto, ON, Canada
Unrau, Jennifer
McLuckie, Duncan
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机构:
Victoria Gen Hosp, Dept Anesthesia, Victoria, BC, CanadaUniv Toronto, Temerty Fac Med, Div Pediat Gen & Thorac Surg, Toronto, ON, Canada
McLuckie, Duncan
Else, Scott
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机构:
Univ Calgary, Cumming Sch Med, Dept Anesthesia, Calgary, AB, CanadaUniv Toronto, Temerty Fac Med, Div Pediat Gen & Thorac Surg, Toronto, ON, Canada
Else, Scott
Brindle, Mary E.
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机构:
Brigham & Womens Hosp, Harvard TH Chan Sch Publ Hlth, Ariadne Labs, Boston, MA USA
Univ Calgary, Cumming Sch Med, Div Pediat Surg, Calgary, AB, CanadaUniv Toronto, Temerty Fac Med, Div Pediat Gen & Thorac Surg, Toronto, ON, Canada