Functional PD-L1 transfer from TLR-Bregs to activated splenic CD4+T cells.

被引:0
|
作者
Liao, Minxue [1 ,2 ,3 ]
Lee, Kang Mi [1 ,2 ]
Katsuhiro, Tomofuji [1 ,2 ]
Deng, Kevin [1 ]
Matheson, Rude [1 ,2 ]
Zhao, Gaoping [4 ]
Deng, Shaoping [4 ]
Lei, Ji [1 ,2 ,3 ]
Markmann, James F. [1 ,2 ,3 ]
机构
[1] Massachusetts Gen Hosp, Ctr Transplantat Sci, Boston, MA USA
[2] Massachusetts Gen Hosp, Dept Surg, Boston, MA USA
[3] Univ Penn, Perelman Sch Med, Philadelphia, PA USA
[4] Univ Elect Sci & Technol China, Sch Med, Chengdu, Peoples R China
关键词
D O I
10.1097/01.tp.0001066860.15409.a5
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
V-311.1
引用
收藏
页数:1
相关论文
共 50 条
  • [31] CD4+T cell activation distinguishes response to anti-PD-L1+anti-CTLA4 therapy from anti-PD-L1 monotherapy
    Franken, Amelie
    Bila, Michel
    Mechels, Aurelie
    Kint, Sam
    Van Dessel, Jeroen
    Pomella, Valentina
    Vanuytven, Sebastiaan
    Philips, Gino
    Bricard, Orian
    Xiong, Jieyi
    Boeckx, Bram
    Hatse, Sigrid
    Brussel, Thomas Van
    Schepers, Rogier
    Van Aerde, Cedric
    Geurs, Sarah
    Vandecaveye, Vincent
    Hauben, Esther
    Poorten, Vincent Vander
    Verbandt, Sara
    Vandereyken, Katy
    Qian, Junbin
    Tejpar, Sabine
    Voet, Thierry
    Clement, Paul M.
    Lambrechts, Diether
    IMMUNITY, 2024, 57 (03) : 541 - 558.e7
  • [32] Intratumoral CD103+CD8+T cells predict response to PD-L1 blockade
    Banchereau, Romain
    Chitre, Avantika S.
    Scherl, Alexis
    Wu, Thomas D.
    Patil, Namrata S.
    de Almeida, Patricia
    Kadel, Edward E., III
    Madireddi, Shravan
    Au-Yeung, Amelia
    Takahashi, Chikara
    Chen, Ying-Jiun
    Modrusan, Zora
    McBride, Jacqueline
    Nersesian, Rhea
    El-Gabry, Ehab A.
    Robida, Mark D.
    Hung, Jeffrey C.
    Kowanetz, Marcin
    Zou, Wei
    McCleland, Mark
    Caplazi, Patrick
    Eshgi, Shadi Toghi
    Koeppen, Hartmut
    Hegde, Priti S.
    Mellman, Ira
    Mathews, W. Rodney
    Powles, Thomas
    Mariathasan, Sanjeev
    Grogan, Jane
    O'Gorman, William E.
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 9 (04)
  • [33] PD-1/PD-L1 expression on CD4+ T cells and myeloid DCs correlates with the immune pathogenesis of atrial fibrillation
    Liu, Li
    Zheng, Qiangsun
    Lee, Jun
    Ma, Zhiqiang
    Zhu, Qiming
    Wang, Zhiquan
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2015, 19 (06) : 1223 - 1233
  • [34] Human colonic myofibroblasts suppress activated CD4+T-cell responses via PD-L1 signaling.
    Pinchuk, Irina
    Soada, Jamal
    Beswick, Ellen
    Suarez, Giovanni
    Adegboyega, Patrick
    Mifflin, Randy
    Reyes, Victor
    Powell, Don
    CLINICAL IMMUNOLOGY, 2006, 119 : S156 - S156
  • [35] TLR9 signalling activation via direct ligation and its functional consequences in CD4+T cells
    Sharma, Ravi Kumar
    Sharma, Jyoti
    Kumar, Rajendra
    Badal, Darshan
    Pattekar, Ajinkya
    Sehgal, Shobha
    Gupta, Amod
    Jain, Pooja
    Sachdeva, Naresh
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2022, 96 (05)
  • [36] Pathogenicity of functionally activated PD-1+CD8+ cells and counterattacks by muscular PD-L1 through IFNγ in myositis
    Sasaki, Hirokazu
    Umezawa, Natsuka
    Itakura, Takuji
    Iwai, Hideyuki
    Yasuda, Shinsuke
    JOURNAL OF AUTOIMMUNITY, 2024, 142
  • [37] PD-1 and PD-L1 Expression in Peripheral CD4/CD8+ T Cells Is Restored in the Partial Remission Phase in Type 1 Diabetes
    Li, Xia
    Zhong, Ting
    Tang, Rong
    Wu, Chao
    Xie, Yuting
    Liu, Fang
    Zhou, Zhiguang
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2020, 105 (06): : 1947 - 1956
  • [38] Egr2-independent, Klf1-mediated induction of PD-L1 in CD4+ T cells
    Shuzo Teruya
    Tomohisa Okamura
    Toshihiko Komai
    Mariko Inoue
    Yukiko Iwasaki
    Shuji Sumitomo
    Hirofumi Shoda
    Kazuhiko Yamamoto
    Keishi Fujio
    Scientific Reports, 8
  • [39] Egr2-independent, Klf1-mediated induction of PD-L1 in CD4+ T cells
    Teruya, Shuzo
    Okamura, Tomohisa
    Komai, Toshihiko
    Inoue, Mariko
    Iwasaki, Yukiko
    Sumitomo, Shuji
    Shoda, Hirofumi
    Yamamoto, Kazuhiko
    Fujio, Keishi
    SCIENTIFIC REPORTS, 2018, 8
  • [40] PD-1/PD-L1 interactions contribute to functional impairment of minor histocompatibility antigen-specific CD8+T-cells targeting PD-L1-expressing leukaemic cells
    Norde, W. J.
    Maas, F.
    Korman, A.
    Quigley, M.
    Kester, M.
    Hebeda, K.
    Falkenburg, J. H. F.
    de Witte, T.
    Schaap, N.
    van der Voort, R.
    Dolstra, H.
    BONE MARROW TRANSPLANTATION, 2011, 46 : S310 - S310