Seroprevalence of Strongyloides stercoralis, human T-lymphotropic virus, and Chagas disease in the Peruvian Amazon: a cross-sectional study

被引：0

作者：

Casapia-Morales, Martin ^{[1
]}

Casanova-Rojas, Wilma-Selva ^{[1
]}

Vazquez-Ascate, Jhosephi ^{[1
]}

Carey-Angeles, Cristiam-Armando ^{[1
]}

Alvarez-Antonio, Carlos ^{[2
]}

Alava-Arevalo, Freddy-Franco ^{[2
]}

Otero-Rodriguez, Silvia ^{[3
,4
]}

Ramos-Rincon, Jose-Manuel ^{[3
,5
]}

机构：

[1] Univ Nacl Amazonia Peruana, Fac Med Humana, Iquitos, Peru

[2] Minist Salud Peru, Iquitos, Peru

[3] Hosp Univ Gen Dr Balmis, Dept Med Interna, Alicante, Spain

[4] Inst Invest Salud & Biomed, Alicante, Spain

[5] Univ Miguel Hernandez Elche, Fac Med, Dept Med Clin, Carretera N-332,S-N,03550 St Joan Alacant, Alicante, Spain

来源：

REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO | 2024年 / 66卷

关键词：

Strongyloides stercoralis; HTLV; Chagas disease; Trypanosoma cruzi; Serology; Sero-prevalence; Prevalence; Peru; Amazon; INDIGENOUS POPULATIONS; TRANSMISSION; PREVALENCE; AMERICA; HTLV-1; RISK;

D O I：

10.1590/S1678-9946202466073

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Strongyloides stercoralis infections, human T-lymphotropic virus (HTLV) infections, and Chagas diseases occur throughout many regions of Central and South America, including Peru. This study aimed to evaluate the seroprevalence of S. stercoralis, HTLV, and Chagas disease in Iquitos (Peruvian Amazon) and the associated epidemiological conditions for S. stercoralis seroprevalence in Iquitos. A population-based cross-sectional study was conducted from May 1 to June 15, 2020, to assess the seroprevalence of S. stercoralis [lysate antigen ELISA (enzyme linked immunosorbent assay)], HTLV (recombinant antigen ELISA), and Chagas disease (crude and recombinant antigen ELISAs). Of the 396 included individuals, 257 were seropositive for S. stercoralis (a 64.9% prevalence, 95% confidence interval [CI] 60.0% to 69.4%). In the multivariable analysis, seropositivity for S. stercoralis was higher in women (odds ratio [OR] 1.60, 95% CI 1.03 to 2.66) and residents of Punchana (OR 3.47, 95% CI 1.51 to 7.93), whereas residence in Iquitos was associated with lower positivity (OR 0.52, 95% CI 0.32 to 0.85). In total, four individuals were positive for HTLV (1.0% seroprevalence, 95% CI 0.3% to 2.7%), and none were positive for Chagas disease (0.0% seroprevalence, 95% CI 0.0% to 1.2%). The seroprevalence of S. stercoralis in Iquitos is high, particularly among women and residents of Punchana. The presence of HTLV infection indicates that the virus is circulating in Iquitos. This study found no cases of Chagas disease.

引用

页数：8