Susceptibility of calf lung slice cultures to H5N1 influenza virus

被引：0

作者：

Guilfoyle, Kate ^{[1
]}

Mirolo, Monica ^{[2
]}

van Amerongen, Geert ^{[1
]}

van der Net, Guido ^{[1
]}

Lombardo, Mara Sophie ^{[2
]}

Stoerk, Theresa ^{[2
]}

Rimmelzwaan, Guus ^{[2
]}

Ludlow, Martin ^{[2
]}

Osterhaus, Albert ^{[2
]}

机构：

[1] Cerba Res, Preclin Special Serv, Viroclin Xplore, Schaijk, Netherlands

[2] Univ Vet Med Hannover, Res Ctr Emerging Infect & Zoonoses, Hannover, Germany

来源：

EMERGING MICROBES & INFECTIONS | 2025年 / 14卷 / 01期

关键词：

Influenza; lung slices; cattle; species susceptibility; HPAI H5N1;

D O I：

10.1080/22221751.2024.2432368

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The current outbreak of HPAI H5N1 virus infections in dairy cattle in the USA underscores the need for easily accessible methods to rapidly assess host susceptibility for infection with known and emerging influenza viruses. Here we show that ex vivo lung slice cultures from calves provide a useful method to rapidly screen host susceptibility to a range of influenza A viruses.

引用

页数：3

共 11 条

[1] Air-Liquid Interface Cultures of the Healthy and Diseased Human Respiratory Tract: Promises, Challenges, and Future Directions [J].

Baldassi, Domizia ;

Gabold, Bettina ;

Merkel, Olivia M. .

ADVANCED NANOBIOMED RESEARCH, 2021, 1 (06)

[2] H5N1 clade 2.3.4.4b avian influenza viruses replicate in differentiated bovine airway epithelial cells cultured at air-liquid interface [J].

Bordes, Luca ;

Gerhards, Nora M. ;

Peters, Stan ;

van Oort, Sophie ;

Roose, Marit ;

Dresken, Romy ;

Venema, Sandra ;

Vrieling, Manouk ;

Engelsma, Marc ;

van der Poel, Wim H. M. ;

de Swart, Rik L. .

JOURNAL OF GENERAL VIROLOGY, 2024, 105 (06)

[3]

CDC, 2024, H5N1 bird flu: current situation. Avian influenza (bird flu)

[4] Pathogenicity and transmissibility of bovine H5N1 influenza virus [J].

Eisfeld, Amie J. ;

Biswas, Asim ;

Guan, Lizheng ;

Gu, Chunyang ;

Maemura, Tadashi ;

Trifkovic, Sanja ;

Wang, Tong ;

Babujee, Lavanya ;

Dahn, Randall ;

Halfmann, Peter J. ;

Barnhardt, Tera ;

Neumann, Gabriele ;

Suzuki, Yasuo ;

Thompson, Alexis ;

Swinford, Amy K. ;

Dimitrov, Kiril M. ;

Poulsen, Keith ;

Kawaoka, Yoshihiro .

NATURE, 2024, 633 (8029) :426-432

[5]

European Food Safety Authority (EFSA), About us

[6] Precision-cut bovine udder slices (PCBUS) as an in-vitro-model of an early phase of infection of bovine mastitis [J].

Filor, Viviane ;

Petry, Monique ;

Meissner, Jessica ;

Kietzmann, Manfred .

BMC VETERINARY RESEARCH, 2021, 17 (01)

[7] H5N1 clade 2.3.4.4b dynamics in experimentally infected calves and cows [J].

Halwe, Nico Joel ;

Cool, Konner ;

Breithaupt, Angele ;

Schoen, Jacob ;

Trujillo, Jessie D. ;

Nooruzzaman, Mohammed ;

Kwon, Taeyong ;

Ahrens, Ann Kathrin ;

Britzke, Tobias ;

Mcdowell, Chester D. ;

Piesche, Ronja ;

Singh, Gagandeep ;

dos Reis, Vinicius Pinho ;

Kafle, Sujan ;

Pohlmann, Anne ;

Gaudreault, Natasha N. ;

Corleis, Bjoern ;

Ferreyra, Franco Matias ;

Carossino, Mariano ;

Balasuriya, Udeni B. R. ;

Hensley, Lisa ;

Morozov, Igor ;

Covaleda, Lina M. ;

Diel, Diego G. ;

Ulrich, Lorenz ;

Hoffmann, Donata ;

Beer, Martin ;

Richt, Juergen A. .

NATURE, 2025, 637 (8047) :903-912

[8] Genomic characterization of highly pathogenic avian influenza A H5N1 virus newly emerged in dairy cattle [J].

Hu, Xiao ;

Saxena, Anugrah ;

Magstadt, Drew R. ;

Gauger, Phillip C. ;

Burrough, Eric R. ;

Zhang, Jianqiang ;

Siepker, Chris ;

Mainenti, Marta ;

Gorden, Patrick J. ;

Plummer, Paul J. ;

Li, Ganwu .

EMERGING MICROBES & INFECTIONS, 2024, 13 (01)

[9]

Karakus U, 2018, METHODS MOL BIOL, V1836, P59, DOI 10.1007/978-1-4939-8678-1_4

[10] Paramyxovirus infections in ex vivo lung slice cultures of different host species [J].

Nguyen, D. Tien ;

de Vries, Rory D. ;

Ludlow, Martin ;

van den Hoogen, Bernadette G. ;

Lemon, Ken ;

van Amerongen, Geert ;

Osterhaus, Albert D. M. E. ;

de Swart, Rik L. ;

Duprex, W. Paul .

JOURNAL OF VIROLOGICAL METHODS, 2013, 193 (01) :159-165

← 1 2 →