Sex differences in donor-site morbidity after microvascular free tissue head and neck reconstruction

被引：0
|
作者：
Teitelbaum, Jordan I. [1 ,2 ]
Choi, David D. [1 ,2 ]
Moreno, Kattia F. [1 ,2 ]
Tabangin, Meredith E. [3 ]
Patil, Yash J. [1 ,2 ]
机构：
[1] Univ Cincinnati Med Ctr Coll Med, Dept Otolaryngol Head, CINCINNATI, OH 45219 USA
[2] Univ Cincinnati Med Ctr, Dept Neck Surg, Coll Med, Cincinnati, OH 45219 USA
[3] Cincinnati Childrens Hosp Med Ctr, Div Biostat & Epidemiol, Cincinnati, OH USA
来源：
JOURNAL OF LARYNGOLOGY AND OTOLOGY | 2025年 / 139卷 / 01期
关键词：
head and neck neoplasm; free tissue flaps; sex characteristics; quality of life; QUALITY-OF-LIFE; FREE-FLAP RECONSTRUCTION; GENDER-DIFFERENCES; CANCER-PATIENTS; COMPLICATIONS; STATISTICS; VALIDITY; SURGERY; IMPACT;
D O I：
10.1017/S0022215124001257
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
Background The purpose of this study is to investigate whether sex plays a role in donor-site dysfunction after head and neck reconstruction.Methods In this retrospective case series, 76 patients were assessed for donor-site morbidity using the Short Form 36, Short Musculoskeletal Function Assessment, disabilities of the arm, shoulder, and hand, and lower-limb core scale. Differences by sex were compared using t-tests. Multivariable linear regression analysis was conducted to adjust for potential confounders.Results Females observed significantly greater disability for the SF-36 mental component summary score with a mean of 45.9 (standard deviation 10.5) compared to males, with a mean of 51.8 (standard deviation 10.2), p = 0.02. Sex is significantly related to SF-36 mental component summary score after controlling for neuropsychiatric disease and tracheostomy status.Conclusion Females reported significantly worse mental component scores compared to males undergoing free flap reconstruction of the head and neck.
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页码：72 / 77
页数：6
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