A lutein and zeaxanthin enriched extra virgin olive oil as a potential nutraceutical agent: A pilot study

被引:1
作者
Martin-Vertedor, Daniel [1 ]
de Valle-Prieto, Maria Benito [1 ]
Garrido, Maria [2 ]
Gil, Ma Victoria [3 ,4 ]
Delgado-Adamez, Jonathan [1 ]
机构
[1] Govt Extremadura, Technol Inst Food & Agr INTAEX, Ctr Sci Res & Technol Extremadura CICYTEX, Avda Adolfo Suarez s-n, Badajoz 06007, Spain
[2] Univ Extremadura, Fac Sci, Dept Physiol, E-06006 Badajoz, Spain
[3] Univ Extremadura, Fac Sci, Dept Organ & Inorgan Chem, E-06006 Badajoz, Spain
[4] Univ Extremadura, Unidad Quim Verde & Desarrollo Sostenible, IACYS, E-06006 Badajoz, Spain
关键词
Extra virgin olive oil; Upgrading; Lutein and zeaxanthin; Antioxidant; Nutraceutical agent; PHENOLIC-COMPOUNDS; CAROTENOIDS; BIOAVAILABILITY; ANTIOXIDANT;
D O I
10.1016/j.foodchem.2024.141811
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Xanthophylls lutein and zeaxanthin are carotenoids with important antioxidant capacities and relevant roles against the prevention of eye diseases. In this study a valorization of non-commercial spinach to obtain lutein and zeaxanthin as raw materials to develop nutraceuticals was carried out. Three oil matrixes were analyzed: extra virgin olive oil (EVOO), lutein and zeaxanthin enriched EVOO (EVOO+LZ), and EVOO enriched with 25 % of EVOO+LZ (namely EVOO+D) to evaluate their biological potential as antioxidants. Urinary antioxidant total capacity, and circulatory blood levels of lutein and zeaxanthin were determined (in vivo analysis). Also, a simulation of gastrointestinal simulation (in vitro analysis) was performed. The results showed an increase in the circulatory levels of lutein-zeaxanthin after the ingestion of EVOO+LZ during 45 and 60 days, and an increase in the urinary antioxidant levels after the intake of EVOO+LZ and EVOO+D. In vitro assay revealed that both xanthophylls showed bioavailability to be assimilated in the intestinal tract. Therefore, these EVOO enriched with lutein-zeaxanthin might be considered as powerful antioxidant tools with potential properties in the management/prevention of eye diseases.
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页数:7
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