Advancements in the study of T lymphocytes in thoracic aortic aneurysm and aortic dissection

被引：0
作者：
Chen, Baolin [1 ,2 ]
Wang, Xueling [1 ,2 ]
Jiang, Bo [1 ,2 ]
Xin, Shijie [1 ,2 ]
机构：
[1] China Med Univ, Affiliated Hosp 1, Dept Vasc Surg, Shenyang, Peoples R China
[2] Key Lab Pathogenesis Prevent & Therapeut Aort Aneu, Shenyang, Liaoning, Peoples R China
来源：
TISSUE & CELL | 2025年 / 93卷
基金：
中国国家自然科学基金;
关键词：
Thoracic aortic aneurysms and dissection; Inflammation; T lymphocytes; Cytokines; Vascular Immunity; CELLS; PATHWAY;
D O I：
10.1016/j.tice.2025.102768
中图分类号：
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号：
100101 ;
摘要：
Thoracic aortic aneurysms and dissection (TAAD) is a critical, life-threatening cardiovascular condition characterized by immune-mediated inflammatory infiltration and structural degradation of the aorta wall, which are pivotal in its etiology. In recent years, the significance of T lymphocytes in TAAD has increasingly garnered scientific attention. TAAD is a multifaceted vascular disorder characterized by the involvement of many immune cells, with T lymphocytes playing a pivotal role, particularly in the modulation of inflammatory responses, immunological control, and tissue damage. A comprehensive understanding of the T lymphocyte activation process in TAAD is crucial for the advancement of novel preventative and therapy strategies. This article evaluates the recent research advancements on the function of T lymphocytes in TAAD, aiming to offer novel insights for the future prevention and treatment of TAAD.
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页数：7
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